Synopsis

The Office of Academic Exchange Programs of the Bureau of Educational and Cultural Affairs announces an open competition to administer the FY2010 Global Undergraduate Exchange Program for Pakistan. Public and private non-profit organizations meeting the provisions described in Internal Revenue Code section 26 USC 501(c)(3) in the United States may submit proposals to organize and carry out academic exchange activities for students from underrepresented sectors in Pakistan. The recipient organization will be responsible for the following aspects of the program: Placement of no less than 100 foreign students at accredited U.S. institutions (50 for fall semester 2010, 50 spring semester 2011) student travel to the U.S., orientation, enrichment programming, advising, monitoring and support, pre-return activities, evaluation, and follow-up with program alumni. Support for this program is being provided from special FY2009/FY2010 supplemental funds that have been appropriated to the Department. It is anticipated that the total amount of funding for FY2010 administrative and program costs will be $2,000,000 pending availability of funds.

Deadline Note

Proposals can be submitted from September 1, 2009 to October 1, 2009 and from January 15, 2010 to February 15, 2010.

Synopsis

The IMEE program focuses on the impact of large-scale hazards on civil infrastructure and society and on related issues of preparedness, response, mitigation, and recovery.

Deadline Note

Proposals are accepted within a window of one month before the deadline date.

Synopsis

The IMEE program focuses on the impact of large-scale hazards on civil infrastructure and society and on related issues of preparedness, response, mitigation, and recovery.

Deadline Note

The January 15 and August 15 target dates refer to regular proposals. The February 15 and October 15 target dates refer to dissertation proposals.

Synopsis

Support is provided for research in sociology.

Deadline Note

Regular Grants are targeted for January 15, 2010. Proposals for Doctoral Dissertation Research Improvement Awards (DDRI) are due by October 15, 2009 and February 15, 2010.

Synopsis

The Geography and Regional Science (GRS) Program sponsors research on the geographic distributions and interactions of human, physical, and biotic systems on the Earth's surface.

Deadline Note

The deadline for pre-proposals is February 15, 2010. Full proposals are due by April 5, 2010.

Synopsis

A -- 2010 TRANSPORTATION PLANNING BROAD AGENCY ANNOUNCEMENT (BAA) - 2010 TRANSPORTATION PLANNING BAA - ATTACHMENTS 1-3 SOL DTFH61-10-R-00013 POC Josph A. Fusari, Phone: 2023664244, Robert G Prior, Phone: 2023664247 WEB: FBO.govPermalink https://www.fbo.gov/spg/DOT/FHWA/OAM/DTFH61-10-R-00013/listing.html E-MAIL: Joseph.fusari@dot.gov, bob.prior@dot.gov Joseph.fusari@dot.gov, bob.prior@dot.gov NAICS: 541712 Attachment 3 - Past Performance Questionnaire Attachment 2 - Prime Contractors Analysis of Subcontractors Costs Attachment 1 - Sample Statement of Work 2010 Transportation Planning BAA BROAD AGENCY ANNOUNCEMENT (BAA) DTFH61-10-R-00013 January 2010 T A B L E O F C O N T E N T S Section Title Page 1 BAA Process Overview 3 2 Focus Areas 5 3 General Proposal Information 7 4 Instructions for Submission of Pre-Proposals 11 5 Pre-Proposal Content 11 6 Pre-Proposal Evaluation 12 7 Instructions for Full Proposals 12 8 Proposal Format 13 9 Evaluation Criteria 16 10 Technical and Cost Negotiations 20 11 Attachments 21 Section 1 BAA Process Overview 1.1 General Information CONTRACTING POINT OF CONTACT: Joseph Fusari Contract Specialist Joseph.Fusari@dot.gov 1.2 Summary of Important Dates This Broad Agency Announcement (BAA) describes a two-phase process forproposal submission and evaluation. In the first phase, short pre-proposals will be submitted for review. The Federal Highway Administration (FHWA) will then ask for full proposals of those pre-proposals that are of interest to FHWA. Further detail on proposal dates are as follows: The FHWA anticipates that the proposal, evaluation and award process for this BAA will proceed generally in accordance with the following schedule: BAA opens (FBO publication) January 5, 2009 Pre-Proposals Due 4:30 EST February 15, 2009 Invitation for Full Proposal March 5, 2009 Full Proposals Due 4:30 EST April 5, 2009 Anticipated Contract Award Date May 30, 2009 Proposals shall be sent by electronic transmission to: Joseph.Fusari@dot.gov. Any questions relating to this announcement must be emailed to the contracting point of contact. No telephonic requests will be taken. 1.3 Definitions Federal Acquisition Regulations (FAR) For additional information visit (http://farsite.hill.af.mil/vffara.htm) Metropolitan Planning Organization (MPO) The forum for cooperative transportation decision-making; required for urbanized areas with populations over 50,000. Office of Planning, Environment, and Realty For additional information visit ( http://www.fhwa.dot.gov/hep/index.htm ) Regional Planning Organization (RPO) A multipurpose organization composed of representativesof local governments and appointed representatives from the geographic area covered by the council, and designated as the primary organization to address problems and plan solutions that are of greater than local concern or scope Research Programs For additional information visit ( http://www.fhwa.dot.gov/hep/research.htm ) Safe, Accountable, Flexible, Efficient Transportation Equity Act: A Legacy for Users (SAFETEA-LU) For additional information visit ( http://www.fhwa.dot.gov/hep/step/index.htm ) 1.4 Background Section 5207 of the Safe, Accountable, Flexible, Efficient Transportation Equity Act: A Legacy for Users (SAFETEA-LU) established the Surface Transportation Environment and Planning Cooperative Research Program (STEP) authorizing funding to support this new program. The general objective of the STEP is to improve understanding of the complex relationship between surface transportation, planning and the environment. Section 5207 of SAFETEA-LU identifies certain characteristics of STEP regarding program contents and administration including: •· Develop more accurate models for evaluating transportation control measures and system designs for use by State and local governments to meet environmental requirements; •· Improve understanding of transportation demand factors; •· Develop indicators of economic, social, and environmental performance of transportation systems to facilitate alternatives analysis; •· Meet additional priorities determined through the transportation research and development strategic planning process identified in section 5208 of SAFETEA-LU; •· Refine the scope and research emphases through outreach and in consultation with stakeholders. Additional information on STEP including resources, research plans, focus areas, and proposal requests are located on page http://www.fhwa.dot.gov/hep/step/index.htm.1.5 Objectives and Description The FHWA, through the Office of Planning, Environment, and Realty is soliciting for proposals for research and development projects that could lead to transformational changes and revolutionary advances for transportation planning in the United States. The objective of this BAA is to advance the practice and application of transportation planning among state, metropolitan, regional, local, and tribal transportation planning governments in response to significant changes in the planning process and to identify new tools, techniques, and approaches that respond to national transportation planning priorities. 1.6 Program Scope The program scope is intentionally ambitious and broad to address the wide spectrum of topics and objectives that the funded investigations can support. This program is intended to spur innovation and focus on high risk and high pay-off research and development projects. Incremental advances, demonstrations of existing technologies or applications of state and metropolitan transportation planning activities are not within the scope of this program. Section 2 FOCUS AREAS 2.1 Focus Areas The FHWA is looking for projects within sevenfocus areas that are of particular strategic interest and relevance. Proposals in these areas are highly encouraged. These areas are consistent with emphasis areas identified for the Surface Transportation Environment and Planning Cooperative Research Program developed under Section 5207 of Safe, Accountable, Flexible, Efficient Transportation Equity Act: A Legacy for Users (SAFETEA-LU); see http://www.fhwa.dot.gov/hep/step/index.htm for more information. Additional information on the planning focus areas are located under the "Research Plans" heading located on page http://www.fhwa.dot.gov/hep/step/plans.htm. The seven focus areasinclude: (2.1.1) Tools and Techniques That Support State and local Planning Capacity Building The FHWA seeks to expand the knowledge, understanding, and implementation of efforts that will advance state and local planning capacity buildingincluding the consideration of audience needs, agency practices, and process requirements in statewide and metropolitan transportation planning. Key emerging planning research issues for State Departments of Transportation (DOT), Metropolitan Planning Organizations (MPO), and small and rural areas could consider: •§ How States, MPO, and Regional Planning Organizations (RPO) and benefit from livability, performance-based planning, asset management, and program cost management, •§ What new and innovative forecasting techniques are available through the development of new process or decision-support tools for planning that can be tailored to multi-use development, program finances and revenue,and coordination with new planning partners, •§ What emerging tools and techniques are available that would assist communities in maintaining their transportation system and more effectively prioritize and limited program resources, and •§ What jurisdictional and institutional issues exist, such asthe development of new planning tools that provide a framework for developing ashared vision for the future by analyzing various forces (e.g., health, transportation, economic, environmental, land use, etc.) that affect growth. •§ How jurisdictional and institutional issues including the development of new planning tools to provide a framework for developing a shared vision for the future by analyzing various forces (e.g., health, transportation, economic, environmental, land use, etc.) and their affects on each other to promote sustainable growth can be addressed. •§ How r egional and local impacts of transportation investments on various sustainability indicators (economy, environment, health, et cetera.) are considered in planning and project selection. (2.1.2) Tools and Techniques That Support Tribal Planning Capacity Building The FHWA seeks to expand the knowledge, understanding, and implementation of efforts that will advance the development of innovative tools or approaches that promote the integration of tribal issues into the transportation planning and programming processes at the State and metropolitan levels. Tribes are not required by law to develop or maintain transportation planning programs. This limits their ability to interface at the same level with States and metropolitan transportation planning and programming efforts minimizing their ability to interface through consultation efforts and their effectiveness when competing for State and metropolitan funding opportunities. Key emerging planning research issues are: •§ Development of "information tools" for Tribal Departments of Transportation can use to improve consultation practices in the statewide and metropolitan transportation planning processes, and •§ Identifying how innovative planning techniques can assist tribes in developing their own transportation planning program using novel processes that apply tools, techniques, and technology specifically designed for tribal transportation planning programs with limited staff and resources. (2.1.3) Global Climate Change and Air Quality Research needs should consider advancing the practice and application of transportation planning among state, regional, and local transportation planning agencies to successfully meet growing concerns about the relationship between transportation, air quality, and climate change. Key emerging research issues to consider include: •§ Howentities can better understand the contribution of transportation facilities and services to air pollution and greenhouse gases and their potential implications, including environmental and human health impacts, •§ How entities can develop and assess analytical methods to adequately identify and reduce transportation emissions that contribute to global climate change, •§ What cost-effective mitigation strategies are available to reduce transportation emissions that contribute to global climate change, •§ How can State DOT'simprove the understanding of climate change impacts on transportation facilities and systems and the ability to consider adaptation and mitigation, •§ How can State DOT's evaluate greenhouse gas mitigation efforts, •§ What new and innovative methods of communicating scientific and regulatory information on transportation-air quality to partners are available at State and localagencies and to stakeholders, and •§ How can State DOT's assess the potential impacts of climate change on transportation; and determine how to avoidand minimize potential climate change impacts during transportation system planning (2.1.4)Congestion Management Congestion Management Systems reflects a substantive shift in perspective and practice to address congestion management through a process that provides for effective management and operations an enhanced linkage to the planning process, and to the environmental review process, based oncooperatively developed travel demand reduction and operational management strategies as well as capacity increases. In support of the reduction of congestion on America's transportation network as well as support other initiatives to linkoperations and transportation planning, key emerging research issues to consider includes: •§ What innovations in congestion pricing and private sector involvement in transportation investment are available, •§ What advanced analysis tools are available for use in the measurement and evaluation of operational improvements and strategies in transportation planning and advance the Congestion Management Process, and •§ Whether new planning tools and programs for understanding, analyzing and responding to congestion problems are available. (2.1.5) Safety Planning Transportation safety planning should include the development and improvement of data collection methods and project selection processes that respond to the needs of planning and safety decision making processes and how helping planning agencies (State DOTs, MPOs, and Tribal Governments) can build their institutional capacity to integrate safety into their transportation planning and decision-making process. (2.1.6) Public Involvement, Environmental Justice, Visualization in Planning There is a continued need for assessing new methods in public involvement and community impact assessment practice. Environmental justice (including disabled and elderly which are 2 groups of individuals rapidly increasing in numbers) and visualization are emerging areas ofresearch and practice for transportation planning practitioners that can be utilized to help convey and obtain technical information with communities that traditionally were not involved in the planning process. Increasing awareness among State DOTs, MPOs, and other government agencies of the importance of ensuring civil rights and environmental justice in the transportation planning process would be beneficial where there is an opportunity to make trade-offs to avoid impacts. Similarity, visualization applied to transportation planning is an emerging area of both research and practice. Stakeholders from State DOTs, MPOs, and otherinterested parties would benefit from knowing how to effectively apply visualization and how it can result in applying new methods of communication between transportation practitioners, decision-makers, and the general public. (2.1.7) Freight Planning Freight movements are growing as a share of transportation system volumes. Key emerging research issues to consider includes: •§ How State DOTs can develop methods for the integration of freight into the transportation planning and programming processes at the State and metropolitan levels, •§ What innovative methods for effectively engaging the private sector freight community into the State and metropolitan planning processes; how parameterssuch as price, travel time, permitting, and user fees affect modal shift; what elasticities are inherent in these parameters; and new approaches for applying benefits/cost analyses of freight projects in the transportation planning process, and •§ How new planning tools and programs such as freight analytical techniques, freight modeling improvements, methods of innovative freight data collection and data sharing can be used. SECTION 3 GENERAL PROPOSAL INFORMATION 3.1 General Information All business and administrative correspondence or questions on this BAA should be directed to the contract specialist identified in section 1. The FHWA has budgeted approximately $1,500,000 for fiscal year 2010 to fund this research announcement. Proposals will be evaluated using a two-part process consisting of pre-proposals and full-proposals. Offerors whose pre-proposalsare of interest to the FHWA will be invited to submit full proposals. The FHWA may select for award all, none, or a subset of the acceptable proposals meeting its needs. The FHWA anticipates making multiple awards, typically of 12-24 months duration with the size of individual awards varying depending on the research area and study requirements. The FHWA strongly encourages cost sharing under anycontract that may result, and can offer cooperative agreements if the proposer can offer a cost share of 50 percent from non-federal sources of funding. The FHWA strongly encourages proposals that offer a significant non-federal matching funds or in-kind resources. Cost reasonableness and realism will also be considered in the overall selection process. Individual proposal evaluations will be based on acceptability or non-acceptability without regard to other proposals submitted under the announcement. Selection will be based primarily on scientific or technical merit, partnership, relevance and importance to agency, and the availability of funds. For cooperative agreements, the Federal share of the cost of a project or activity carried out under this program is limited by Section 5101(b)of SAFETEA-LU to fifty (50) percent, unless otherwise determined by the Secretary of Transportation. The number of awards, and their dollar value, will vary depending on the merit of proposals received and their potential to lead to transformational changes and advances in transportation planning practice. Offerors should prepare proposals with a baseline period of performance of 12-24 months and, if needed, with one or more options up to an additional 24-month period of performance. 3.2 Note: Not all technically meritorious proposals may be funded due to budgetary constraints. 3.3 Pre-Proposal and Full Proposal Process Proposals may respond to one or more of the focus areas but must indicate which area is primary and which area or areas are subordinate. Organizations also may submit morethan one proposal when the proposed effort includes multiple disparate objectives and tasks, covers multiple or disparate technologies areas, or would have a more supportable budget if provided in parts; however, each proposal will be considered independently. Proposals will be evaluated using a two-part process consisting of a pre-proposal and a full-proposal. The FHWA will evaluate pre-proposals against the evaluation criteria outlined below. Those offerors whose pre-proposals are of interest may be invited to submit a formal full-proposal. Offerors whose pre-proposals are determined not to be of interest are not precluded from submitting a full proposal and may do so if they desire. Approximately thirty (30) days after the pre-proposal submission deadline, offerors submitting pre-proposals will be contacted with a letter informing them either that the FHWA is requesting a formal cost and technical proposal or that the effort proposed is not of interest to the Government. 3.4 Other Administrative Information Proposals that plan to collect information from more than 9 non-Federal entities may require the FHWA to obtain clearance prior to the commencement of any information collection (Approximate time for clearance, 6 months). Awards involving any Privacy Act-covered data will require special clearances and protections. It is the policyof the FHWA to treat all proposals as competitive information and to disclose the contents only for the purposes of evaluation. Only Government evaluators willmake selections under this BAA. This announcement constitutes the public announcement as contemplated by FAR 6.102(d)(2), and no formal Request for Proposals or other solicitation regarding this announcement will be issued. Requests for same will be disregarded. 3.5 Deliverables The specific deliverables will depend upon the scope and objectives of the negotiated award. At a minimum, the contractor shall present results for at least one peer review and submit a final report,with a technical summary, that documents the research conducted in each task identified in the proposal. Additional deliverables such as interim reports, documentation, and instrumentation could be required and the specific deliverables will be identified in the negotiated statement of work. 3.6 Period of Performance The base contract period of performance is negotiable, but shall be no more than24 months from date of award. 3.7 Optional Future Phase or Phases Proposals mayinclude a discussion of work products for an optional, future phase or phases of work for up to an additional 24 months (up to three more pages). Such discussion shall be clearly labeled as "optional future phase or phases of work." The original phase or work shall in no way depend on work described under future phases in order to meet the program criteria. If a future phase or phases are included, a separate budget shall be included for the phase or phases and be labeled clearly as "separate budget for optional future phase or phases." 3.8 Pre-Proposaland Full Proposal Information The Government reserves the right to select for award any, all, part, or none of the proposals received in response to this announcement. In addition, the Government reserves the right to award either contracts, grants, or other instruments determined to be of benefit to the government inachieving the goals of this program. This BAA is an expression of interest onlyand does not commit the Government to pay any direct pre-proposal or proposal preparation costs. All responsible sources capable of satisfying the Government'sneeds may submit proposals, which will be evaluated. Historically Black Colleges and Universities (HBCU) and Minority Institutions (MI) are encouraged to submit proposals and join others in submitting proposals. However, no portion of thisBAA will be set aside for HBCU and MI participation due to the desire to solicit ideas as broadly as possible. The FHWA has budgeted approximately $1,500,000 to fund this research program. Proposals will be evaluated using a two-part process consisting of pre-proposals and full-proposals. Offerors whose pre-proposals are of interest to the FHWA will be invited to submit full proposals. The FHWA may select for award all, none, or a subset of the acceptable proposals to construct a balanced program meeting its needs. The FHWA anticipates making multiple awards from the $1,500,000, typically of an 16-18 month duration. Note: Awards with a total value (including full period of performance and any option periods) of $100,000 and below will be issued as purchase orders. Note: Awards over $100,000 will be issued as contracts or cooperative agreements. The FHWA strongly encourages cost sharing under any contract that may result, and can offer cooperative agreements if the proposer can offer a cost share of 50 percent or greater from non-federal sources of funding. For cooperative agreements, the Federal share of the cost of a project or activity carried out under this program is limited by Section 5101(b) of SAFETEA-LU to fifty (50) percent, unless otherwise determined by the Secretary of Transportation. The number of awards, and their dollar value, will vary depending on the merit of proposals received and their potential to lead to transformational changes and advances in transportation planning practice. Offerors should prepare proposals with a baseline period of performance of18 months and, if needed, with one or more options up to an additional 24-monthperiod of performance. The scope of this announcement is intentionally broad toinvite innovation and to provide the FHWA the flexibility to sponsor research that best addresses its objectives. In keeping with FHWA's desire for innovation and flexibility, the specific approach in the selected full proposals will vary and will be negotiated. Any resulting contracts will contain appropriate federalagency clauses for the type of procurement vehicle awarded. Prior to award, theOfferor shall be required to submit "Certifications and Representations." Data and reporting requirements will be negotiated with the offeror (s) selected for award(s). The proposal submission shall be conducted in two phases: •1. Pre-proposal for FHWA review •2. Full Proposal. Proposals may respond to one or more of the subject areas but must indicate which area is primary and which area or areas are subordinate. Organizations also may submit more than one proposal when the proposed effort includes multiple disparate objectives and tasks, covers multiple or disparate technologies areas, or would have a more supportable budget if provided in parts; however, each proposal will be considered independently. Proposals will be evaluated using a two-part process: pre-proposals and full-proposals. The FHWA will evaluate pre-proposals against the evaluation criteria outlined above. Those offerors whose pre-proposals are of interest may be invited to submit a formal full-proposal, as described below. Offerors whose pre-proposals are determined not to be of interest are not precluded from submitting a proposal and may do so if they desire. Approximately thirty (30) days after the pre-proposal submission deadline, offerors submitting pre-proposals will be contacted by the Technical Point of Contact with a letter informing them either thatthe FHWA is requesting a formal cost and technical proposal or that the effort proposed is not of interest to the Government. The FHWA strongly encourages proposals that offer a significant non-federal matching funds or in-kind resources. Good proposals will evidence strong internal backing with matching funds, innovative approaches in contracting and leveraging current and past technology development efforts that support this program. Such proposals will receive consideration in addition to and above how they respond to the technical criteria above. Cost reasonableness and realism will also be considered in the overall selection process. Individual proposal evaluations will be based on acceptability or non-acceptability without regard to other proposals submitted under the announcement. Selection will be based primarily on scientific or technical merit, partnership,relevance and importance to agency, and availability of funds. Section 4 4.1 Pre-Proposal Instructions Pre-proposals must be submitted via electronic mail and must be received on or before 4:30 PM (EST), February 15, 2010. Facsimile transmissions or hard copy transmissions of the pre-proposal will not be accepted; so any sent will be disregarded. Pre-proposals shall be submitted via email to: Joseph.Fusari@dot.gov. SECTION 5 CONTENT OF PRE-PROPOSALS 5.1 Content of Pre-Proposals Proposals should be submitted in Microsoft Word 2003 or Adobe Portable Document Format. The pre-proposals shall be no longer than 7 pages in length and include the following 7 sections: Page 1 shall include proposal information including (a) the Broad Agency Announcement Number, (b) project title, (c) name of organization, (d) name of principle investigator(s), (e) phone and addresses for bothtechnical and business contacts; and (f) the identification of the primary subject area and subordinate subject area or areas, if any, the proposal addresses. Pages 2 & 3 shall provide a brief statement of objectives, narrative to demonstrate an understanding of current practices, trends and future needs, and major intended tasks and proposed deliverables. Page 4 shall describe how the research would provide value to advancing practitioners involved in Statewide, metropolitan, rural, regional, local, or Tribal transportation planning. Page 5 shall describe how the research will respond to current or future needs in Statewide, metropolitan, rural, regional, local, or Tribal transportation planning. Page 6 shallintroduce the research team, their general qualifications and other resources to accomplish the proposed effort. Page 7 shall outline a draft budget (includingthe use of matching non-federal funds and resources, if applicable) The budget shall further include the anticipated period of performance and any anticipated option periods, and partnership/subcontractor structures. Offerors should refer to the Evaluation Criteria below to ensure that their pre-proposal addresses theFHWA's requirements. SECTION 6 EVALUATION CRITERIA OF PRE-PROPOSALS 6.1 Evaluation Criteria The primary basis for selecting pre-proposals will be technical merit, importance to the FHWA programs, and the availability of funds. Technical merit will be evaluated based on the following criteria, listed below in descending order of importance: Category I: Category I proposals are well-conceived, scientifically/ technically sound, pertinent to program goals/objectives, and offered by a responsible offeror. Category I proposals are recommended for full proposal (subject to availability of funds) and normally will be displaced only by other Category I proposals. Category II: Category II proposals are scientifically or technically sound that may require further development. They can be recommended for full proposal, but are a lower priority than Category I. Category III: Category III proposals are not technically sound or do not meet agency needs. Proposals in this category are not recommended for full proposal. SECTION 7 INSTRUCTIONS FOR SUBMISSION OF FULL PROPOSALS 7.1 Full Proposal Instructions After the pre-proposals evaluation stage is complete, offerors who are invited to submit full proposals will be notified of the actual dates for submission and will provided with specific instructions for submission of full proposals. Offerors who choose not to submit a pre-proposal, but who wish to submit a full proposal may do so, without invitation. It is presently anticipated that full proposals will include a technical proposal that is 20 pages or less in length, as well as a separate appropriate cost proposal. Offerors submitting full proposals will be asked to submit technical proposals that provide a refined research problem statement and work scope, a management plan, technology transition plan, staffing qualifications, and information regarding other ongoing research and work. In addition tothe technical proposal, offerors will be requested to submit a cost proposal that provides complete and detailed budget information (length as necessary), information on proposed cost sharing, and other general business information. If necessary, the FHWA will request additional cost back-up information, resumes or supplemental information as appropriate. Recipients of cooperative agreements willbe asked to complete the applicable SF-424series of forms Each Offeror shall submit their proposal electronically in Microsoft Office 2003 or equivalent formats. The evaluation board may take into account when making its evaluation, any failure to conform to the instructions and rules in this section or any attempt toevade these specifications and rules on the basis of technicalities, as indicators of future performance. If an Offeror does not understand the instructions asdescribed herein, then they must submit their questions(s) to the Contract Specialist (Joseph Fusari) for clarification sufficiently in advance of the deadlinefor the receipt of offers to get an answer in time to meet that deadline. 7.2 Questions on the BAA content, issues, or procedures should be emailed to: Joseph.Fusari@dot.gov. 7.3 Proposal Due Date Proposals are due by 4:30 pm EST on April 5, 20 10 electronically to: Joseph.Fusari@Dot.gov Offers must be received by thetime and due date specified herein to be considered timely and acceptable. SECTION 8 Proposal Format 8.1 Proposal Format Full proposals shall be submitted by an authorized representative and include a technical proposal 20 pages or less inlength, a separate cost proposal, resumes, and past performance. The technical proposal shall include the following four (4) sections and subsections: Part I Technical Proposal (1) Cover Page with (A) the BAA number, (B) proposal title, (C) type of business (large business, small disadvantaged business, other small business, HBCU or MI, other educational, or other nonprofit), (D) complete list ofsubcontractors, (E) technical and administrative points of contact including addresses, telephone numbers, electronic mail addresses, and facsimile machine numbers. (2) Refined research problem statement (up to three pages) with a description of the proposed visionary technology or system and how the proposed effort will meet the objectives of the broad agency announcement, a comparison of these innovative ideas with current approaches and the current state of the art and the expected impact of the research if successful. (3) Complete work scope (up to five pages) describing research methods, steps, schedule (for a period of performance up to two years) with milestones, expected deliverables and associated evaluation metrics for the proposed effort. (4) A Management Plan (no more than onepage) describing the overall approach to management of this effort, including abrief discussion of the proposed organization and the use of personnel and other resources. This section should also describe the partnership structure betweenthe entity proposing work and other public and private sector entities funding or otherwise substantially participating in the work, including State Departments of Transportation, State Air Quality Agencies, Metropolitan Planning Organizations, Universities, Foundations, etc. (5) A Technology Transition Plan (no more than one page) describing the how the research could be transferred into local or national practice. (6) Facilities: (no more than one page) describing the facilities that would be used for the proposed effort. (7) All work plans must include preparation of read-ahead documents, presentation materials, meeting facilities, and a two day presentation to a peer review panel of the base year validation results and plans for modeling scenarios implementation and scenario evaluation plans. In addition, at least one web conference will be subsequently held to respond to reviewer comments and present scenario evaluation findings. Members ofthe peer review will be identified in cooperation with FHWA. FHWA will arrange for peer travel and related expenses (8) The work plan shall clearly indicate how the proposed effort will lead to transformational changes and revolutionary advances for transportation planning. The work plan shall describe the necessary tasks required to support the proposed work. The work plan shall describe a timeline for completion of each task and the interrelationships of all tasks. Part II Staffing Proposal : (1) Research team qualifications (up to three pages) with title and identification of association to a specific project or functional group within the proposing organization or to a specific proposed subcontractor. Indicate the proposed amount of effort (person-hours) to be expended by each person during the proposed program. (2) As part of its proposal, the offeror shall designate a Project Manager and other personnel deemed by the offeror to be essential to the successful completionof the contract. These individuals will be listed in the contract as Key Personnel. In the event any of the Key Personnel are unable to perform as proposed forany reason during the performance of the contract, the contractor shall immediately notify the COTR and Contacting Officer in writing. Such notice will includean explanation of the problem, a proposed replacement by someone of equal or better qualifications and experience, and shall explain the impact on performance.All replacements are subject to the prior written approval of the Contracting Officer. However, the Government reserves the right to approve such replacements retroactively when circumstances prevent advance approval. Part III Past Performance/Experience (1) Reference to past relevant research at the national, state or regional level (up to two pages) describing capabilities, work, and significant accomplishments in areas associated with proposed research area or in closely related areas. Associate the described relevant experience to the specific project group or functional group in the proposing organization or to the specific proposed subcontractor(s). (2) Other proposals (one page maximum) summarizing current and pending proposals being executed or proposed to be executed with the support of personnel proposed in this effort. This list should include project scale, start and end dates, and the average amount of time planned or currently being expended on each effort. The list should be organized by names of the key personnel and other significant senior personnel. If none, state none under this section. (3) A Bibliography (one page maximum) of relevant technical papers and research notes which support the technical concepts and innovative ideas described in this proposal. Part IIII Cost Proposal (1) In addition to the above 20-page or shorter technical proposal, offerors shall submit a cost proposal that provides complete budget information (length as necessary). A separate summary budget shall be provided for the base period and for each proposed option period. Each summary budget shall include costs by each major cost category such as direct labor, fringe benefits, subcontracts, travel and other direct costs, overhead/indirect costs, and fee (if applicable). Direct labor information shall provide detail regarding each proposed individual or labor category, the number of hours or percent of time proposed for each period, and the unburdened hourly rate or salary for each person or category. For other direct costs (travel, materials and supplies, etc), provide detail and explanation for how each element of cost was derived and estimated. For any subcontracts, provide a separate detailed budget forthe subcontract work, and provide a price analysis of the work. Please note that the FHWA can pay per diem for travelers, but cannot pay for special meals or receptions under contracts. Only small printing/duplicating costs should be proposed, if needed; any large printing jobs must be carried out by the FHWA in accordance with Government Printing Office regulations. A separate detailed cost breakdown shall also be provided by task and subtask, using the same task or subtasknumbers as described in the scope of work in the technical proposal. If necessary, the government will request additional cost back-up information, resumes or supplemental information as appropriate. Details of any cost sharing to be undertaken by the offeror shall also be included in the cost section. Describe the type of funds (cash, in kind, etc.), and its contribution and relationship in enhancing the proposed effort. With the budget include the following mandatory business information regarding your company: Business Size; Federal Tax Identification Number (TIN); Dun & Bradstreet Number; Name and contact information (mail address, telephone, and email address) of your authorized business representative/point of contact. An SF1411, Contract Pricing Proposal Cover Sheet, is not required for this submission of your proposal. (2) An estimated budget and spending plan for completion of the project must be clearly labeled and identified in the cost proposal. 8.2 Subcontractors Subcontractors' proposals must be similarly structured. All subcontracted work must be properly identified as such. If a subcontractor elects to submit an abbreviated proposal, it is the offeror's responsibility to see that the subcontractor submits the information requested in paragraph 4(e)(1) or (2) above and submits the proposal directly to the Government's point of contact. The offeror must ensure that the subcontractor adheres to the guidance set forth herein. FAR 15.404-3 requires that the offeror provide an analysis of subcontractors' cost proposals. To that end, offeror's proposal must:(1) Identify principal items/services to be subcontracted. (2) Identify prospective subcontractors and the basis on which they were selected. If non-competitive, provide selected source justification (3) Identify the type of contractual business arrangement contemplated for the subcontract and provide a rationale for same. (4) Identify the basis for the subcontract costs (e.g., firm quote or engineering estimate, etc). (5) Identify the cost or pricing data or information other than cost or pricing data submitted by the subcontractor. (6) Provide an analysis of the proposed subcontract in accordance with FAR 15.404-3(b). Provide an analysis concerning the reasonableness, realism and completeness of each subcontractor's proposal. If the analysis is based on comparison with prior prices, identify the basis on which the prior prices were determined to be reasonable. The analysis should include, but not be limited to, an analysis of: materials, labor, travel, other direct costs and proposed profit or fee rates. A guide as to howthe analysis may be performed is located on Attachment No. 2. i. Changes to Pricing Proposals: Changes to previously submitted proposals must include documentation indicating how a previously submitted proposal is impacted or affected. (1)If changes to the original proposal are relatively insignificant and involve only minor changes to elements such as labor rates, overhead and General and Administrative (G&A) rates, bill of material changes, travel costs, and Other Direct Costs (ODC's), these change can be accomplished through the use of change pages or slip pages accompanied by new cost summaries. 8.3 NOTE: The requirements of Section 508 of the Rehabilitation Act may apply to certain deliverables under anyresulting award, including the final report. The applicability of Section 508 will be determined on a case-by-case basis depending on the nature of deliverables under each award that results from this BAA. 8.4 NOTE: Rights to copyrightablesoftware delivered under any resulting award of this BAA shall be determined inaccordance with 48 CFR 52.227-14 and alternatives I, II, III. Furthermore, all software deliveries, preliminary and final, will include as a minimum, well-documented source code in electronic readable format, overall software architecture documentation, overall and individual module interface documentation, and a users operations manual. All hardware deliveries will include all documentation necessary to reproduce (assemble) and operate the delivered hardware system(s). Also, if applicable, provide a summary of any proprietary claims to results, software, hardware, prototypes, or systems supporting and/or necessary for the use of the research, results, software, hardware, prototype, or system proposed for development under this broad agency announcement. If there are no proprietary claims, this section shall consist of a statement to that effect. SECTION 9 EVALUATIONCRITERIA OF FULL PROPORALS 9.1 Evaluation Criteria The primary basis for selecting proposals will be technical merit, importance to the FHWA programs, and the availability of funds. Technical merit will be evaluated based on the following criteria, listed in descending order of relative importance: Full proposals willbe evaluated based on the following criteria in descending order of importance below. 1. Technical Approach (55 points) •a. Provides a sound, feasible, and achievable technical approach. Discusses the steps (or tasks) to execute the methodology by which the project objective will be achieved (25 points) •b. Discusses and demonstrates the ability to clearly describe the project objectives, needs, and the manner in which they will be addressed. Te chnical approach issound, feasible, and achievable. (20 points) •c. Demonstrates a solid grasp of the subject area; familiarity with regulatory or programmatic issues. (10 points) 2. Staffing (45 points) •a. Includes the academic credentials, professional experience, subject matter expertise and technical competence of key personnel for this project, including all the personnel who will participate as subcontractors for this project (25 points) •b. Discusses the research team's relevant skills and experience that will ensure success. Provide a short bio andlist of relevant experience for each technical personnel. (15 points) •c. Provides contingency plans in place to replace key personnel over the life of the project without any adverse impact on performance (5 points) Evaluation Scale Outstanding Excellent Good Fair Poor Unsatisfactory 55 points 55 44 33 22 11 0 45 points 45 36 27 18 9 0 25 points 25 20 15 10 5 0 20 points 20 16 12 8 4 0 15 points 15 12 9 6 3 0 10 points 10 8 6 4 2 0 5 points 5 4 3 2 1 0 Outstanding - Very comprehensive, in-depth, clear response. The Proposal consistently meets thisstandard with no omissions. Consistently high quality performance can be expected. Excellent - Extensive, detailed response similar to outstanding in quality, but with minor areas of unevenness or spottiness. High quality performance is likely but not assured due to minor omissions or areas where less than excellent performance might be expected. Good - No deficiencies in the response. Better than acceptable performance can be expected, but in some significant areas, there is an unevenness or spottiness that might impact on performance. Fair - Deficiencies are confined to areas with minor impact on performance and can be corrected during negotiation without major revision to the proposal. Poor - Deficiencies exist in significant areas but can be corrected during negotiations without majorrevision to the proposal or serious deficiencies exist in areas with minor impact. Unsatisfactory - Serious deficiencies exist in significant areas. The proposal only indicates a willingness to perform without specifying how or demonstrating the capability to do so. Only vague indications of capability are present. 3. Past Performance •a. Demonstrated successful experience and examples in developing, deploying, and delivering improved and/or new tools, techniques, and procedures to support the project being proposed. •b. Includes examples of successful performance in prior contracts. The Government will evaluate the merits of each offeror's past performance based on its reputation with its former customers including some or allof the following past performance areas: (1) Quality of Service; (2) Timelinessof Performance; (3) Price/Cost Control; and (4) Customer Satisfaction. Evidencecan include references, samples of correspondence from satisfied clients, letters of recommendation, etc. In conducting the past performance evaluation, the Government may use information obtained from other sources. The Government may consider the currency, degree of relevance, source, and context of the past performance information it evaluates as well as general trends in performance, and demonstrated corrective actions. A significant achievement, problem/problem resolution, or lack of relevant data in any element can become an important consideration in the selection process. A negative finding in any element may result in an overall high-risk rating. The Government may also consider past performance information regarding predecessor companies, key personnel, other corporate entities or subcontractors where such information is relevant to this acquisition. Offerors' past performance will be rated as follows: Very Low Risk: Based on the offeror's past performance, very little doubt exists that the offeror will successfully perform the required effort. Low Risk: Based on the offeror's past performance, little doubt exists that the offeror will successfully perform the required effort. Moderate Risk: Based on the offeror's past performance, some doubt existsthat the offeror will successfully perform the required effort. High Risk: Based on the offeror's past performance, significant doubt exists that the offeror will successfully perform the required effort. Neutral Risk: The offeror has little or no recent/relevant past performance upon which to base a meaningful performance risk evaluation. The Government is not required to interview all points ofcontact identified by offerors. It is the responsibility of the offeror to provide complete past performance information and thorough explanations as required by Section L. The Government is not obliged to make another request for the required information. 9.2 Non-federal matching funds The FHWA strongly encourages proposals that offer a significant non-federal matching funds or in-kind resources. Good proposals will evidence strong internal backing with matching funds, innovative approaches in contracting and leveraging current and past technology development efforts that support this program. Such proposals will receive consideration in addition to and above how they respond to the technical criteria above. Cost reasonableness and realism will also be considered in the overall selectionprocess. Individual proposal evaluations will be based on acceptability or non-acceptability without regard to other proposals submitted under the announcement. Selection will be based primarily on scientific or technical merit, partnership, relevance and importance to agency, and availability of funds. Note that all technically meritorious proposals may not be funded due to budgetary constraints. In addition to the criteria listed above, cost/price will be considered in theaward decision. The proposals will be analyzed to assess their price reasonableness. This means that the prices in an offeror's proposal are realistic for the work to be performed, reflect a clear understanding of the requirements, and areconsistent with the various elements of the offeror's technical proposal. The Government will accept the offer that is considered the best value to the Government. A best value analysis will be performed taking into consideration the results of the technical evaluation, cost and past performance analysis, and the perceived ability to perform timely, high quality, consistently reliable support services as provided herein. In the determination of Best Value, the relative weight given to all evaluation factors other than price, when combined, is more important than price. However, offerors should note that as technical scores approachbeing essentially equivalent, cost would become more important in the selectiondecision. 9.3 Administrative Information It is the policy of the FHWA to treat all proposals as competitive information and to disclose the contents only for the purposes of evaluation. Only Government evaluators will make selections underthis BAA. This announcement constitutes the public announcement as contemplatedby FAR 6.102(d) (2), and no formal Request for Proposals or other solicitation regarding this announcement will be issued. Requests for same will be disregarded. The Government reserves the right to select for award any, all, part, or noneof the proposals received in response to this announcement. In addition, the Government reserves the right to award either contracts, purchase orders, or otherinstruments determined to be of benefit to the government in achieving the goals of this program. This BAA is an expression of interest only and does not commit the Government to pay any pre-proposal or proposal preparation costs. All responsible sources capable of satisfying the Government's needs may submit proposals, which will be evaluated. Historically Black Colleges and Universities (HBCU) and Minority Institutions (MI) are encouraged to submit proposals and join others in submitting proposals. However, no portion of this BAA will be set aside forHBCU and MI participation due to the desire to solicit ideas as broadly as possible SECTION 10 TECHNICAL AND COST NEGOTIATIONS 10.1 Contact Vehicle The Contract Officer will determine the appropriate award vehicle depending on the work to be performed and notify the offeror of his/her decision. 10.2 Model Proposal Once the proposal evaluation is completed and ranked, the offerors selected for negotiations are notified by letter, email or phone by the Contracting Officer. If necessary, this notification letter may include further instructions. The written notification shall also include a model contract. The model contract provides the basis for negotiations on all contractual requirements, terms, and conditions. If the offeror takes exception to any requirements, these must be specifically identified in the reply to the Contracting Officer. The reply must also include any other information required by the Government. 10.3 Revised or Updated CostProposal If necessary, at the same time an offeror is notified of their selection, they may be requested to submit either an updated or revised cost proposal and any additional cost information or backup cost data. 10.4 Technical Proposal Changes Normally, if any clarifications are needed by the Government technical evaluators, the offeror will be contacted before completion of the evaluation andreceipt of the notification letter. However, a proposal may be selected for negotiations although additional technical data is still required. If this occurs, the Government negotiator will request any technical documentation needed. 10.5 Buying Part versus All Normally an entire proposed effort is purchased; however,the FHWA may from time to time be interested in acquiring part or parts of a proposal. This is one reason the Government requires offerors to write the SOW in the form of separate tasks. It facilitates evaluation and provides an easy way to select desired tasks. If the FHWA decides to buy only part or parts of a proposal, the notification letter may request the offeror to revise the cost proposalto reflect only what will be purchased. SECTION 11 ATTACHMENTS 1•1. SampleStatement of Work •22. Prime Contractors Analysis of Subcontractors Costs •33. Past Performance Questionnaire CITE: https://www.fbo.gov/?s=opportunity&mode=form&id=ac164c8ae3c75df21e8786c2b9383d90&tab=core&_cview=0 Posted 01/05/10 (W-SN02034808). (0005)

Deadline Note

Optional letters of intent are due on February 15, 2010. Full applications are due on April 27, 2010.

Synopsis

The purpose of this project is to support state, major urban, and tribal public health agencies, national organizations and state coalitions to improve maternal, infant, child, and reproductive health through the application of evidence-based approaches. Additionally, as one of the goals of the Division of Reproductive Health is to promote partnerships at the local, state, tribal, and national levels, this project highlights the importance of engaging partners in the applied sciences process including analysis of relevant data, interpretation of results, and translation of findings to public health practice.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after February 16, 2010. The deadline for receipt of optional letters of intent is February 16, 2010. The deadline for receipt of full applications is March 15, 2010.

Synopsis

The sponsor invites projects that address research endeavors in specific areas that will benefit from significant three-year funds without the expectation of continued NIH funding beyond this period. The research supported by the program should have high short-term impact, and a high likelihood of enabling growth and investment in biomedical research and development, public health, and health care delivery. Applicants may propose to address either a specific disease- or technology-related research question relevant to the mission of one or more participating Institutes and Centers, or propose the creation of a unique infrastructure/resource designed to accelerate scientific progress in the future. All NIH Institutes and Centers with funding authority will participate with the NIH Office of the Director in this initiative. This FOA will be administered by the Office of the Director of the NIH (http://www.nih.gov). Awards will be administered by the participating Institutes and Centers. This FOA will utilize the NIH RC4 award mechanism.

Deadline Note

This program will expire on May 8, 2010.

Synopsis

The sponsor offers support for Small Research Grant (R03) applications. The R03 grant mechanism supports different types of health services research projects including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and, development of new research technology.

Synopsis

B -- CULTURAL RESOURCES SUPPORT SERVICES MULTIPLE AWARD TASK ORDER CONTRACT (PRESOL) SOL W912EP-10-R-0006 DUE 012610 POC Jennifer Robar, 904-232-2814 POP USArmy Engineer District, Jacksonville P.O. Box 4970, Jacksonville FL 32232-0019 WEB: FBO.gov Permalink https://www.fbo.gov/spg/USA/COE/DACA17/W912EP-10- R-0006/listing.html E-MAIL: US Army Engineer District, Jacksonville jennifer.l.robar@usace.army.mil NAICS: 541990 The Government intends to issue a solicitation from which up to three (3) Indefinite Delivery Indefinite Quantity (IDIQ) Contracts will be awarded under a Multiple Award Task Order Contract (MATOC), provided sufficient qualified contractors present offers. The Government reserves the right to award less than three (3) contracts based upon its discretion. The life of the contract will be for a base period of one year from date of award, with options to extend four (4) additional one-year periods, not to exceed a total of five years. The contractors selected to receive an award will share the total capacity of approximately $6.5M. Contractors selected to receive award under this MATOC will be given an opportunity to submit a proposal on Task Orders in accordance with Federal Acquisition Regulation 16.505(b). Task Orders issued under this MATOC will be firm fixed price awards. Description of Work: The work to be performed is expected to vary for each Task Order. A Performance Work Statement (PWS) shallbe provided with each individual Task Order request for proposal. Depending upon the requirements of each Task Order, the requirements will include, but are not limited to the following: execute background/archival investigations, culturalresources field investigations, process, describe, and analyze data using appropriate laboratory methods, and prepare graphically illustrated, scientifically acceptable written reports of such studies and analyses. Field investigations will normally be conducted in Florida, Puerto Rico and the U.S. Virgin Islands. Specific project areas will be defined in individual Task Orders. The Contractor may be required to conduct field investigations, attend meetings and submit reports and deliverables to various locations in or beyond Florida, Puerto Rico, and the U.S. Virgin Islands, as specified in each Task Order. All work will be conducted in compliance with the National Historic Preservation Act of 1966 (PL 89-665) as amended, the Archeological Resources Protection Act of 1979 (PL 96-95), the Archeological and Historic Preservation Act of 1974 (PL 93-291) as amended, the Native American Graves Protection and Repatriation Act of 1990 (PL 101-601), the National Environmental Policy Act of 1969 (PL91-190), and their implementing regulations, and shall be performed by professionals meeting the appropriate qualifications established in Archeology and Historic Preservation: Secretary of theInterior's Standards and Guidelines (48 FR 44716, Sept 29, 1983) as found at: http://www.nps.gov/history/local-law/arch_stnds_0.htm. THIS ACQUISITION IS SET ASIDE FOR SMALL BUSINESSES UNDER NAICS CODE 541990. The Government will use a bestvalue Performance Price Trade-off (PPT) evaluation process in accordance with Federal Acquisition Regulation (FAR) Part 15.101- 1.The factors to be evaluated will include technical merit, past performance and price. The decision to award will be based upon offers from responsible contractors that conform to the requirements of the solicitation and offer the best overall value to the Government. Solicitation W912EP-10-R-0006 will be issued on or around 28 December 2009 with offers due on or about 26 January 2010. Note: The Response Date referenced under General Information is estimated. Information on the EXACT PROPOSAL DUE DATE willbe stated in the solicitation. Solicitation will be issued in electronic formatonly and will be posted on the Army Single Face to Industry (ASFI) website at https://acquisition.army.mil/asfi/. In order to receive notification of any amendments to this solicitation, interested vendors must REGISTER AS AN INTERESTED VENDOR on the Federal Business Opportunities website at http://www.fedbizopps.gov/. If you are not registered, the Government is not responsible with providing you with notification of any changes to this solicitation. You must be registered in the Central Contractor Registration in order to be eligible to receive an award from this solicitation. Call 1-888- 227-2423 for more information or visit theCCR website at http://www.ccr.gov. You also must be registered in Online Representations and Certifications Application (ORCA) in order to receive an award from this solicitation. The ORCA website is located at http://orca.bpn.gov. NAICS Code is 541990, small business size standard is $7 million. E-MAIL LINK: Jennifer.L.Robar@usace.army.mil CITE: https://www.fbo.gov/?s=opportunity&mode=form&id=ff327ebb34a80c073928a05316cf8b 70&tab=core&_cview=0 Posted 12/14/09 (W-SN02023529). (0348)

Synopsis

The sponsor solicits competitive proposals from eligible organizations to enter into cooperative agreements to outreach to the small business community in their designated region and provide financial and technical assistance, business training programs, such as, business assessment, management training, counseling, technical assistance, marketing and outreach, and the dissemination of information, to encourage and assist small businesses to become better prepared to compete for, obtain, and manage sponsor funded transportation-related contracts and subcontracts at the federal, state and local levels.

Synopsis

This program provides grants for capital improvements, and related infrastructure improvements at qualified shipyards that will be effective in fostering efficiency, competitive operations, and quality ship construction, repair, and reconfiguration.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after May 18, 2009. The deadlines for receipt of standard R21 applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2012.

Synopsis

The sponsors invite applications for basic, pre-clinical, and clinical complementary cancer research. The research should relate to the areas of prevention, diagnosis, and treatment of cancer as well as management of cancer symptoms and side effects due to conventional cancer treatment. In addition, this FOA encourages the development and application of emerging and innovative technologies, including identification of novel therapeutics in the pharmacopoeia of Traditional Medical Systems (as defined by the World Health Organization), use of complementary approaches to improve the therapeutic ratio of standard and investigational anti-cancer therapies, and research on lifestyle modifications (e.g. diet, exercise, mind-body approaches) for their impact on cancer outcomes (e.g., response to conventional cancer therapy, survival). The overarching goals of this FOA is to encourage investigators to submit high quality, preliminary research of humans that will advance the science of Complementary and Alternative Medicine (CAM) and provide a solid foundation and justification for future research project (R01) grant applications to definitively determine the efficacy of CAM approaches. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after May 16, 2009. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2012.

Synopsis

The sponsors invite the submission of applications in developmental and formative behavioral research in cancer prevention and control. This FOA will support innovative pilot projects or feasibility studies, which will facilitate the growth of research science in the cancer control continuum from a behavioral perspective. This FOA includes and incorporates the research interests of the Behavioral Research program, the Office of Cancer Survivorship, and the Community Oncology and Prevention Trials Research Group. This FOA is appropriate for testing timely interventions in pilot studies for feasibility or using rigorous qualitative research methods to assess the potential efficacy of an intervention. It is also appropriate for the psychometric evaluation of new measures or culturally appropriate ones to be adapted for use in populations where measures have not yet been developed or validated. This FOA encourages applications that include small cross-disciplinary teams of investigators who bring perspectives from the behavioral and social sciences, as well as other fields of public health. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after September 16, 2009. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2012.

Synopsis

The sponsors invite applications for clinical and preclinical research to determine how diet and dietary factors, including dietary supplements, impact DNA methylation, histone posttranslational modification, noncoding RNA, and other epigenetic processes involved in cancer prevention and development. Another important aim of this FOA is to encourage collaborations between nutrition and epigenetic experts to study bioactive food components with cancer-preventative properties and to examine key epigenetic events in cancer processes (e.g., carcinogen metabolism, cell division, differentiation, and apoptosis) in order to begin to establish linkages between epigenetics, methylation patterns, and tumor incidences/behaviors. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after January 16, 2010. The deadlines for receipt of standard R01 applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on January 8, 2013.

Synopsis

The sponsors invite applications that propose to: (1) conduct evaluation research on obesity-related “natural experiments” (defined here as community and other population-level public policy interventions that may affect diet and physical activity behavior), and/or (2) develop and/or validate relevant community-level measures (instruments and methodologies to assess the food and physical activity environments at the community level). The overarching goal of this FOA is to inform public policy and research relevant to (1) diet and physical activity behavior, and (2) weight and health outcomes of Americans. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after January 16, 2010. The deadlines for receipt of standard R01 applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on January 8, 2013.

Synopsis

The sponsors invite applications that propose to: (1) conduct evaluation research on obesity-related “natural experiments” (defined here as community and other population-level public policy interventions that may affect diet and physical activity behavior), and/or (2) develop and/or validate relevant community-level measures (instruments and methodologies to assess the food and physical activity environments at the community level). The overarching goal of this FOA is to inform public policy and research relevant to (1) diet and physical activity behavior, and (2) weight and health outcomes of Americans. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after January 16, 2010. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on January 8, 2013.

Synopsis

The sponsor invites research applications that propose to evaluate profiles of methylation, histone modifications and micro RNA (miRNA) and their association with risk of developing cancer in different populations. The overarching goal of this FOA is to provide support for population based studies to define the role of epigenetic markers (methylation, histone and micro RNA profiles) changes to understand cancer etiology. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after January 16, 2010. The deadlines for receipt of standard R01 applications under this announcement are: February 16, June 16 and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on January 8, 2013.

Synopsis

The sponsors invite applications that propose to: (1) foster multidisciplinary research that will evaluate how policies (federal, state and school district levels) can influence school physical activity and nutrition environments, youths’ obesogenic behaviors (e.g., nutrition and physical activity behaviors), and weight outcomes; (2) understand how schools are implementing these policies and examine multi-level influences on adoption and implementation at various levels (e.g., federal, state, school district, and school); and (3) understand the synergistic or counteractive effect of school nutrition and physical activity polices on the home and community environment and body weight. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after January 16, 2010. The deadlines for receipt of standard R01 applications under this announcement are: February 16, June 16 and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on January 8, 2013.

Synopsis

The sponsors invite applications that propose to: (1) foster multidisciplinary research that will evaluate how policies (federal, state and school district levels) can influence school physical activity and nutrition environments, youths’ obesogenic behaviors (e.g., nutrition and physical activity behaviors), and weight outcomes; (2) understand how schools are implementing these policies and examine multi-level influences on adoption and implementation at various levels (e.g., federal, state, school district, and school); and (3) understand the synergistic or counteractive effect of school nutrition and physical activity polices on the home and community environment and body weight. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2011.

Synopsis

The sponsor offers support for research to: improve the measurement of racial /ethnic discrimination in health care delivery systems through improved instrumentation, data collection and statistical/analytical techniques; enhance understanding of the influence of racial/ethnic discrimination in health care delivery and its association with disparities in disease incidence, treatment and outcomes among disadvantaged racial/ethnic minority groups; and reduce the prevalence of racial/ethnic health disparities through the development of interventions to reduce the influence of racial/ethnic discrimination on health care delivery systems in the United States. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

This program will expire on September 8, 2011.

Synopsis

The sponsors offer support for individual-investigators or small groups to collaborate with the NIH Roadmap for Medical Research National Centers for Biomedical Computing (NCBCs). The intention of the collaborating projects is to engage researchers across the nation in building an excellent biomedical computing environment, using the computational tools and biological and behavioral application drivers of the funded NCBCs as foundation stones. This FOA is intended to support exploratory biomedical informatics and computational biology research—applications should be innovative, with high risk/high impact in new areas that are lacking preliminary data or development. This program will use the NIH Exploratory/Developmental (R21) grant mechanism. This PAR is developed as a Roadmap affiliated initiative.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after January 16, 2009. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on January 8, 2012. Electronic application submission is required for this FOA. The new Adobe versions of the application forms are not yet available. Please check back in December to download the application package.

Synopsis

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on November 6, 2011.

Synopsis

The sponsor offers support for projects that enhance the state-of-the-science on the causes of obesity and to inform Federal decision making on effective public health interventions for reducing the rate of obesity in the United States. This FOA is also intended to promote collaborative activities between researchers trained in economics and researchers specializing in public health, cancer, cardiovascular diseases, and other chronic diseases so that the desired goals can be more efficiently, quickly, and successfully attained. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

This program will expire on January 8, 2011.

Synopsis

The sponsor offers support for research projects that will enhance understanding of human decision-making processes so that individuals can make more informed and satisfying choices regarding their health. The NCI encourages collaborations between basic judgment and decision-making researchers, and applied cancer control researchers that will elucidate single-event decision-making processes at the level of the individual patient or health care provider that are pertinent to cancer prevention, detection, treatment, survivorship, or end-of-life care. For the purpose of this initiative, a single-event decision is defined as a discrete decision made at a specific point in time. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after February 5, 2008. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2011.

Synopsis

The sponsor offers support for research to: improve the measurement of racial /ethnic discrimination in health care delivery systems through improved instrumentation, data collection and statistical/analytical techniques; enhance understanding of the influence of racial/ethnic discrimination in health care delivery and its association with disparities in disease incidence, treatment and outcomes among disadvantaged racial/ethnic minority groups; and reduce the prevalence of racial/ethnic health disparities through the development of interventions to reduce the influence of racial/ethnic discrimination on health care delivery systems in the United States. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after May 16, 2009. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on March 6, 2009.

Synopsis

The sponsors applications that propose multidisciplinary research on potential reduced-exposure tobacco products, both smoked and smokeless. The multidisciplinary studies can span basic, biological, behavioral, surveillance, and epidemiology research. The tobacco industry is currently promoting several new products with claims that they: a) are less either harmful or less addictive; and b) purportedly deliver lower amounts of toxic, carcinogenic, and/or addictive agents to the user compared with conventional products. However, to date, the scientific evidence is insufficient to evaluate whether these new products actually reduce the users’ exposure or risk for tobacco-related diseases. The overarching goal of this FOA is to determine whether potential reduced-exposure tobacco products provide a truly, less-harmful alternative to conventional tobacco products, both at the individual and population level. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

This program will expire on January 8, 2011.

Synopsis

The sponsors offers support aimed at enhancing nanoscience and nanotechnology research focused on problems in biology and medicine. Nanoscience and nanotechnology refer to research and development on the understanding and control of matter at a length scale of approximately 1 - 100 nanometers, where novel properties and functions occur because of the size. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2011.

Synopsis

The sponsors provide support for hypothesis-driven projects exploring associations between the built environment, other contextual features of where people of all ages live and work and health behaviors related to energy balance. These projects should use population level data from health surveys and other large health studies. It is expected that the proposed projects will be designed to add/include contextual variables at diverse levels of geographic aggregation to such studies on behaviors that affect individual energy balance and thereby health. Subsequent analyses should be aimed at understanding the relative importance of the contextual variables (including home, work, school, and/or other environments) as determinants of energy balance-related health behaviors. Grant applications will be expected to use population level data from diverse sources for: 1) generation and addition of new geographic information system (GIS) data layers for analysis of contextual variables such as measures of the built and natural environments, to existing studies; 2) analyses of existing confidential geographic-based data either on site, at survey data centers, or other protected sites; and/or 3) merging multiple health-related data resources to allow new analyses of associations between contextual variables and energy balance-related health behaviors. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after September 16, 2008. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 16, 2011.

Synopsis

The sponsors provide support for research projects focused on the development and implementation of effective communication strategies related to diet and health. Specifically, this FOA is designed to promote interdisciplinary research, conducted at multiple levels (e.g., individual, community/environment, and policy) and across diverse populations, to evaluate effective communication approaches for changing dietary behaviors. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after September 5, 2009. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2012.

Synopsis

The sponsors invite applications that propose research on the roles of nutrition and physical activity in the development, prevention, and management of cardiovascular diseases (CVD) or pulmonary diseases. In particular, the FOA aims to (1) improve knowledge of the contribution of diet and physical activity to these conditions and how sleep influences these relationships, (2) increase the evidence base for refining public health recommendations and clinical guidelines regarding these lifestyle behaviors, and (3) develop and test strategies to improve the adoption of these recommendations. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

This program will expire on January 8, 2011.

Synopsis

The sponsors provide support for applications from institutions/organizations that propose to study the ethical, legal and social implications (ELSI) of human genome research. This announcement is specifically designed to: 1) encourage the development of small, focused research projects by legal, historical, ethics, humanities, social sciences and behavioral scholars; 2) support exploratory studies that may provide preliminary findings or pilot data for larger research proposals; 3) support the secondary analysis of existing data; 4) support the development of new methodologies; and 5) stimulate and facilitate the entry of promising new investigators into ELSI Research. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16 and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on January 8, 2011.

Synopsis

The sponsors provide support for innovative high risk/high payoff research related to genomics, including analysis of genome structure and function, genetic variation, population genomics, and ELSI (ethical, legal, and social implications). NHGRI places a high priority on research projects that address technology and methods development in all relevant areas, new approaches to bioinformatics that facilitate data management and data dissemination, new computational biology approaches to data analysis, new strategies to apply genomics to clinical problems, new approaches that combine genomics and population studies, and studies of the ethical, legal and social implications of genomics research including the exploration of new policy approaches to address social issues raised by new capabilities in genomics. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

This program expires September 8, 2012

Synopsis

The sponsor provides support for research related to occupational safety and health. Eligible applicants are domestic and foreign for-profit or non-profit organizations, public or private institutions, such as universities, colleges, hospitals, and laboratories, units of state and local governments, eligible agencies of the federal government, faith-based or community based organizations, and Indian Tribes, Tribal Government, and/or Organizations. The R21 award mechanism will be used.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after May 5, 2009. This FOA will expire on September 8, 2012.

Synopsis

The sponsor provides support for projects designed to develop an understanding of the risks and conditions that are associated with occupational diseases and injuries, to explore methods for reducing risks and for preventing or minimizing exposure to hazardous conditions in the workplace, and to translate significant scientific findings into prevention practices and products that will effectively reduce work-related illnesses and injuries. The R03 grant mechanism supports different types of projects including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. The R03 is intended to support small research projects that can be carried out in a short period of time with limited resources. This FOA will utilize the NIH Small Research Grant (R03) award mechanism,

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after January 16, 2009. The deadlines for receipt of standard R01 applications under this announcement are: February 5, June 5, and October 5 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. . Electronic application submission is required for this FOA. The new Adobe versions of the application forms are not yet available. Please check back in December to download the application package. This program will expire on January 8, 2012.

Synopsis

The sponsor invites R21 research grant applications that will inform interventions addressing the cultural and structural factors that produce high rates of unintended pregnancy across the reproductive age span, especially in low-income populations in the United States. These interventions can operate at a wide range of levels, from clinical interventions to interventions that influence cultural, economic, social, structural, and/or policy factors contributing to unintended pregnancy. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after May 18, 2009. The deadlines for receipt of standard R21 applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2012.

Synopsis

The sponsors invite investigator-initiated research grant applications from institutions/ organizations that propose to conduct behavioral and/or biomedical research aimed at better understanding the etiologies and precursors for, reducing risk for, and incidence of, teen dating violence (TDV). Research is also sought that examines the linkages and gaps among perceptions of appropriate responses to teen dating violence from service providers, the criminal justice system, teens themselves, victims, perpetrators and bystanders. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after May 16, 2009. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2012.

Synopsis

The sponsors provides support to enhance childhood obesity research by fostering the formation of local, state, or regional teams consisting of researchers, policymakers, and other relevant stakeholders (e.g., community representatives, public health practitioners or officials, educators) in order to identify research questions and hypotheses, design and implement the relevant research, and translate the research into evidence relevant to potential policy efforts in this area. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on January 8, 2011.

Synopsis

The sponsors provide support for investigator-initiated research grant applications that seek to develop a comprehensive program of research focused on the mechanisms through which social, economic, cultural, and community-level factors, and their interactions, impact the early cognitive, neurobiological, socio-emotional, and physical development of children. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 2, May 1, and September 1 annually. This program will expire on March 17, 2010.

Synopsis

The sponsor offers support for Small Research Grant (R03) applications from institutions/organizations that propose basic, clinical or translational research on the effects of the Fragile X pre-mutation on ovarian function, with a focus on premature ovarian failure or early menopause, in women and/or animal models. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after January 16, 2008. This program will expire on January 8, 2011.

Synopsis

The sponsor provides support for applications from institutions/ organizations that propose to better understand the role of adipose tissue in the normal physiological regulation of reproduction, to discern its possible role in the etiology of diseases and disorders that impact human fertility, and to probe its potential importance in different racial/ethnic prevalence rates of certain reproductive disorders.This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2011.

Synopsis

The sponsors provide support for Research Project Small Grant applications from institutions/ organizations that propose to enhance our understanding of effective positive youth development programs and the mechanisms responsible for positive health and developmental outcomes. This will be accomplished through the development, implementation, and evaluation of new or improved positive youth development programs, the evaluation of existing “successful” programs, or the evaluation of effective, evidence-based, gender-inclusive programs that are adapted, translated, or disseminated for new populations of youth and adolescents. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2010.

Synopsis

The sponsor offers support for preliminary data collection, pilot or feasibility studies on oral health promotion research directed at improving oral health across the lifespan. The study team must include health promotion, behavioral and/or social scientists. This research on prevention of oral diseases and/or their sequelae could focus in any of the following areas: maternal and child health; adolescent and young adult health; and the health of adults with complex diseases in the general population or in subgroups of the population with health disparities. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2010.

Synopsis

The sponsor offers support for formation of partnerships and/or coalitions among stakeholders to develop a comprehensive research plan on health promotion for a specific oral disease or condition. The partnership or coalition should include individuals with extensive experience in health promotion, behavioral and/or social sciences. This plan would be based on previously collected epidemiological, behavioral, social and/or environmental data and the proposed research plan will inform a subsequent full scale R01-type study. The health research plan could address any of the following areas: a) apply or adapt existing behavioral or health promotion theories and planning research models to known risk factors and lifestyle aspects of oral diseases and conditions, b) promote optimal oral health of individuals, families and communities in the context of overall health and co-morbidities, and c) integrate oral health promotion into general health promotion programs. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Synopsis

The sponsor requests applications for the Hispanic-Serving Institutions Education Grants Program (HSI) for fiscal year (FY) 2010 to promote and strengthen the ability of Hispanic-Serving Institutions to carry out higher education programs that attract, retain, and graduate outstanding students capable of enhancing the nation’s food, agricultural, and natural resource scientific and professional work force. NIFA anticipates the total amount available for support of the HSI in FY 2010 will be approximately $9.2 million.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after September 16, 2009. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2012.

Synopsis

The sponsors invites applications for research and developments in computational science and technology that will support rapid progress in areas of scientific opportunity in biomedical research. As defined here, biomedical computing or biomedical information science and technology includes database design, graphical interfaces, querying approaches, data retrieval, data visualization and manipulation, data integration through the development of integrated analytical tools, and tools for electronic collaboration, as well as computational and mathematical research including the development of structural, functional, integrative, and analytical models and simulations. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Synopsis

The sponsor is seeking applications for funding research and development to enhance forensic crime scene examinations and forensic medicolegal death investigations.

Deadline Note

The deadline to register with GMS and to submit applications is February 16, 2010.

Synopsis

The sponsor seeks proposals for research and development to enhance crime laboratories’ ability to identify, characterize, capture, visualize, and preserve impression evidence and pattern evidence.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after May 18, 2009. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2012.

Synopsis

The sponsor provides support to encourage research on: the development and/or pilot testing of new or adapted interventions; the adaptation and/or pilot testing of interventions with demonstrated efficacy for use in broader scale effectiveness trials; or innovative services research directions that require preliminary testing or development. NIMH intervention and services research is aimed at preventing or ameliorating mental disorders, emotional or behavioral problems, the co-occurrence of mental, physical and substance abuse problems, HIV infections, and the functional consequences of these problems across the life span. This FOA will utilize the NIMH R34 award mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after May 16, 2009. The deadlines for receipt of standard R21 applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2012.

Synopsis

The sponsor provides support for research on women's mental health in relation to pregnancy and the postpartum period. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after January 16, 2009. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on January 8, 2012.

Synopsis

The sponsors solicit collaborative preliminary intervention studies to evaluate the feasibility, tolerability, acceptability and safety of novel mechanism drug candidates, promising investigational new drugs (INDs), or novel psychosocial strategies for the treatment of mental disorders and for obtaining the preliminary data needed as a pre-requisite to larger-scale (efficacy or effectiveness) intervention or services studies. This FOA should be used when at least two but no more than three sites are needed to complete the study. The collaborating studies should be organized in order to increase sample size, accelerate recruitment, and/or increase sample diversity and representation. For a linked set of collaborative R34s, each site shall have its own Project Director/Principal Investigator and provide for a mechanism for cross-site coordination, quality control, database management, statistical analysis, and reporting. This FOA will utilize the NIMH Collaborative R34 award mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after May 16, 2009. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2012.

Synopsis

The sponsor provides support for research on women's mental health and sex/gender differences in mental health. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after January 16. 2010. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. Optional letter of intent may be submitted 30 days prior to the anticipated receipt date. This program will expire on January 8, 2013.

Synopsis

The sponsor invites applications that will identify, develop, and refine effective and efficient methods, structures, and strategies to disseminate and implement research-tested health behavior change interventions and evidence-based prevention, early detection, diagnostic, treatment, and quality of life improvement services into public health and clinical practice settings. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after January 16, 2010. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. Optional letters of intent may be submitted 30 days prior to the anticipated receipt date. This program will expire on January 8, 2013.

Synopsis

The sponsor invites applications that will identify, develop, and refine effective and efficient methods, structures, and strategies to disseminate and implement research-tested health behavior change interventions and evidence-based prevention, early detection, diagnostic, treatment, and quality of life improvement services into public health and clinical practice settings. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2010.

Synopsis

The sponsor provides support for applications that investigate the role of microRNAs and other noncoding RNAs in the etiology of mental disorders. The data generated by this effort will contribute to the disaggregation of the molecular machinery underlying mental disorders by integrating sequence specific modulators of post-transcriptional gene expression into a theoretical framework of disease pathophysiology, with the aim of rapid, widespread sharing of the resulting data to accelerate genetic analysis of human diseases. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after April 7, 2008. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on January 8, 2011.

Synopsis

The sponsors provide support for interdisciplinary studies addressing the psychosocial and behavioral consequences of HIV disease. Over the past decade, secondary prevention in HIV disease, or “positive prevention”, has received a much needed increase in attention. Gains have been made toward the aim of decreasing HIV transmission behaviors and improving quality of life among individuals living with HIV/AIDS, as well as understanding factors that are important to healthy coping. In this program announcement, further opportunities for innovation in this field are indicated. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on January 8, 2011.

Synopsis

The sponsors provide support for interdisciplinary studies addressing the psychosocial and behavioral consequences of HIV disease. Over the past decade, secondary prevention in HIV disease, or “positive prevention”, has received a much needed increase in attention. Gains have been made toward the aim of decreasing HIV transmission behaviors and improving quality of life among individuals living with HIV/AIDS, as well as understanding factors that are important to healthy coping. In this program announcement, further opportunities for innovation in this field are indicated. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2011.

Synopsis

The sponsors provide support for collaborations for exploratory and developmental work on HIV/AIDS in the low and middle income countries of the Middle East and North Africa (MENA), as defined by the World Bank: Algeria, Djibouti, Egypt, Iran, Iraq, Jordan, Lebanon, Libya, Morocco, Oman, Syria, Tunisia, West Bank and Gaza, and Yemen. Specific areas of research include, but aren’t limited to, epidemiologic studies, prevention research from both biomedical and social/behavioral perspectives, studies of social factors affecting the spread of HIV in the region, and research on women and youth. Collaborations must involve U.S. investigators from a partnering U.S. organization and one or more research teams in the MENA region. The collaborative effort supported through the R21 should help foster the development of HIV-relevant research infrastructure and expertise in the region and have the potential to lead to further research and improvements in public health. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after September 16, 2009. The deadlines for receipt of standard R21 applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2012.

Synopsis

The sponsors invite applications from institutions/ organizations that propose to develop new small molecule probes for investigating biological function in the nervous system via the application of advanced medicinal chemistry and the biological testing of compounds. Eligible investigators will have identified probe candidates via screening of small molecule collections, using in vitro assays of biological activity developed to interrogate these collections, and be able to show that the structural features of these small molecules are related to their biological activity. Proposals should nominate small molecule probe candidates from distinct structural series for the further, iterative design and testing of analogues in structure-activity relationship studies, using in vitro assays of biological function adapted to the medium throughput screening requirements of this work. These studies should have the goal of developing a small molecule probe possessing the attributes (eg: affinity, selectivity, activity) required for its use in future pharmacological studies proposed by the investigator. Applicants are strongly encouraged to utilize publicly available cheminformatic capabilities for the acquisition of compounds, and semi-custom synthesis of analogues. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on January 8, 2012.</p>

Synopsis

The sponsors provide support for research that addresses the underlying neurobiological mechanisms associated with cognitive impairment and mood disturbance in Parkinson's disease (PD), that address the development of clinical interventions and therapeutics for cognitive impairment and affective symptoms in PD, or that promote improved clinical diagnosis or treatment of cognitive and affective impairment in PD. A goal of this FOA is to begin a process where basic and clinical scientists from various disciplines can overcome barriers to cross-disciplinary and biobehavioral research and examine all aspects of cognition and affective regulation in the context of the diagnosis and treatment of Parkinson's disease. This PA will use the NIH R21 award mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2011.

Synopsis

The sponsor provides support for research aimed at developing and or refinement of animal or ex vivo cell culture model systems for study of the neurologic complications of AIDS, with or without a history of drug or alcohol use. Recent advances in the development of the SIV model system highlight the power of animal model systems for study of the mechanisms underlying the pathology associated with lentiviral infection in the nervous system. These models will be key for developing therapeutic approaches for the treatment of patients suffering from NeuroAIDS and for understanding the basic biology of infection with HIV/AIDS. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after January 16, 2010. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on January 8, 2013.

Synopsis

The sponsors invite applications to stimulate and foster a wide range of basic, clinical, and translational studies on pain as they relate to the missions of these ICs. New advances are needed in every area of pain research, from the micro perspective of molecular sciences to the macro perspective of behavioral and social sciences. Although great strides have been made in some areas, such as the identification of neural pathways of pain, the experience of pain and the challenge of treatment have remained uniquely individual and unsolved. Furthermore, our understanding of how and why individuals transition to a chronic pain state after an acute insult is limited. Research to address these issues conducted by interdisciplinary and multidisciplinary research teams is strongly encouraged, as is research from underrepresented, minority, disabled, or women investigators. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after January 16, 2010. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on January 8, 2013.

Synopsis

The sponsors invite applications to stimulate and foster a wide range of basic, clinical, and translational studies on pain as they relate to the missions of these ICs. New advances are needed in every area of pain research, from the micro perspective of molecular sciences to the macro perspective of behavioral and social sciences. Although great strides have been made in some areas, such as the identification of neural pathways of pain, the experience of pain and the challenge of treatment have remained uniquely individual and unsolved. Furthermore, our understanding of how and why individuals transition to a chronic pain state after an acute insult is limited. Research to address these issues conducted by interdisciplinary and multidisciplinary research teams is strongly encouraged, as is research from underrepresented, minority, disabled, or women investigators. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after May 16, 2009 .The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2012.

Synopsis

The sponsor offers support for research on the decision-making processes made by persons faced with life-threatening illness. These illnesses are ones that almost always lead to death in a fairly short period of time if left untreated, but may be chronic – or even cured – if dealt with early in the disease process. An example of a life-threatening illness that may be chronic for some years would be HIV infection when treated. An example of a life-threatening illness that may be cured in its early stages would be breast cancer. Decision-making can occur from the point of adopting preventive behaviors through the end of life. Examples of such decisions could include participating in an HIV vaccine clinical trial, testing for genetic disorder, choosing a treatment intervention vs. watchful waiting (as in early stage prostate cancer), choosing a treatment intervention among several options, joining a therapeutic clinical trial, or making end-of-life care decisions. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after May 16, 2009. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2012.

Synopsis

The sponsor offers support for applications that propose to foster biobehavioral research and develop innovative research designs, methods of measurement, and data analysis techniques. Designs and methods that examine the impact of biologic and behavioral variables on individuals' health outcomes and quality of life are encouraged. Scientists are encouraged to increase the interface of biobehavioral research and clinical practice in existing core and exploratory centers and training programs by sharing findings and designing collaborative research projects. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2011.

Synopsis

The sponsor offers support for grant applications from applicant organizations that propose to (a) identify and assess biobehavioral interactions among two or more related and co-occurring symptoms; (b) characterize mechanisms and pathways underlying the symptom interactions; (c) elucidate the level of interaction necessary for categorization as a symptom cluster; and/or (d) design and test interventions targeted to interacting or clustered symptoms that are hypothesized to lead to beneficial patient outcomes. A rationale for the choice of symptoms is needed, not just co-occurrence of two or more symptoms, and they must be associated with a target disease or syndrome or its treatment. Studies at any point in the disease trajectory, or during the survivorship period are encouraged. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2010.

Synopsis

The sponsors provide support for research to reduce health disparities among minority and underserved children. Specifically, this initiative focuses on ethnic and racial minority children and underserved populations of children such as: children from low literacy, rural and low-income populations, geographically isolated children, hearing and visually impaired children, physically or mentally disabled children, children of migrant workers, children from immigrant and refugee families, and language minority children. Specific targeted areas of research include biobehavioral studies that incorporate multiple factors that influence child health disparities such as biological (e.g., genetics, cellular, organ systems), lifestyle factors, environmental (physical and family environments), social (e.g., peer influences), economic, institutional, and cultural and family influences; studies that target the specific health promotion needs of children with a known illness and/or disability; and studies that test and evaluate the cost effectiveness of health promotion interventions conducted in nontraditional settings. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2011.

Synopsis

The sponsors solicit applications from applicant organizations to develop theoretically grounded approaches to prevention of HIV infection and transmission that incorporate biobehavioral approaches in studies that are culturally appropriate. Biobehavioral approaches may be biomedical, or they may consist of behavioral interventions using biological markers of efficacy. Sociocultural appropriateness involves, at minimum, application of knowledge of the norms, beliefs and values of potential research subjects in varied contexts, and an appreciation of culture as dynamic. It is anticipated that such knowledge will improve both the quality and applicability of research among the diverse populations affected by the pandemic, in the US or abroad. Intervention and pre-intervention studies are welcomed, but descriptive ethnographic and epidemiological research is still needed in some areas. For example, descriptive research may delineate the impact of cultural variables on behaviors that impede or promote biological markers (e.g., seroconversion), lead to a better understanding of ethical concerns in biomedical preventive studies, or may illuminate as yet unrecognized issues concerned with adherence to a prevention interventions. Intervention studies should evaluate the efficacy of biomedical interventions, or of behavioral interventions that also use biological variables, in light of the sociocultural context. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. Electronic application submission is required for this FOA. The new Adobe versions of the application forms are not yet available. Please check back in December to download the application package. This program will expire on January 8, 2012.

Synopsis

The sponsors invite applications that address clinical and translational medical issues in the diagnosis and/or management of HIV infection and its consequences in older persons. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. Electronic application submission is required for this FOA. The new Adobe versions of the application forms are not yet available. Please check back in December to download the application package. This program will expire on January 8, 2012.

Synopsis

The sponsors invite applications that address clinical and translational medical issues in the diagnosis and/or management of HIV infection and its consequences in older persons. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after May 18, 2009. The deadlines for receipt of standard R01 applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2012.

Synopsis

The sponsors invite applications that propose basic, clinical, and translational research on chronic kidney disease (CKD) and its consequences in aging and in older persons. Applications should focus on the 1) biology and pathophysiology of CKD in animal models; 2) etiology and pathophysiology of CKD in the elderly; 3) epidemiology and risk factors for the development of CKD with advancing age; and/or 4) diagnosis, medical management and clinical outcomes of CKD in this population. Research supported by this initiative should enhance knowledge of CKD and its consequences in the elderly and provide evidence-based guidance in the diagnosis, prevention, and treatment of CKD in older persons. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after September 16, 2009. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2012.

Synopsis

The sponsors invite applications from institutions/organizations that propose to (1) study biological, neurobiological, psychosocial, and clinical mechanisms and processes by which aging and/or age-related diseases affect the experience of pain, (2) examine biological, neurobiological, psychosocial, and clinical factors that impact pain experience and prevalence in older people, (3) evaluate existing pain assessment and/or management approaches in older adults, or (4) develop new assessment methods and/or management strategies for pain with particular attention to the needs of older adults. Studies involving animal models or human subjects are appropriate under this program announcement. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after September 16, 2009. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2012.

Synopsis

The sponsors invite applications from institutions/organizations that propose to (1) study biological, neurobiological, psychosocial, and clinical mechanisms and processes by which aging and/or age-related diseases affect the experience of pain, (2) examine biological, neurobiological, psychosocial, and clinical factors that impact pain experience and prevalence in older people, (3) evaluate existing pain assessment and/or management approaches in older adults, or (4) develop new assessment methods and/or management strategies for pain with particular attention to the needs of older adults. Studies involving animal models or human subjects are appropriate under this program announcement. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after September 16, 2009. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2012.

Synopsis

The sponsors invite applications proposing to study bioenergetic factors underlying increased fatigability and activity limitations in aging. Increased fatigability is a significant cause of restricted physical and cognitive activity in older adults. Alterations in bioenergetics—the production and utilization of energy, and the regulation of these processes—may contribute significantly to increased fatigability. This FOA encourages applications that propose to 1) elucidate specific alterations in bioenergetics related to increased fatigability and activity limitations; 2) develop and evaluate improved measures of fatigability related to bioenergetics; 3) evaluate interventions for increased fatigability and activity limitations that target alterations in bioenergetics and lead to improved quality of life. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after September 16, 2009. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2012.

Synopsis

The sponsors invite applications proposing to study bioenergetic factors underlying increased fatigability and activity limitations in aging. Increased fatigability is a significant cause of restricted physical and cognitive activity in older adults. Alterations in bioenergetics—the production and utilization of energy, and the regulation of these processes—may contribute significantly to increased fatigability. This FOA encourages applications that propose to 1) elucidate specific alterations in bioenergetics related to increased fatigability and activity limitations; 2) develop and evaluate improved measures of fatigability related to bioenergetics; 3) evaluate interventions for increased fatigability and activity limitations that target alterations in bioenergetics and lead to improved quality of life. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2010.

Synopsis

The sponsor offers support for research designed to stimulate and facilitate data archiving and development related to cognitive psychology, behavioral interventions in the context of randomized controlled trials (RCTs), demography, economics, epidemiology, behavioral genetics and other behavioral research on aging for secondary analysis. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after September 16, 2007. This program will expire on July 17, 2010.

Synopsis

The sponsor provides support for ex ante or ex post harmonization of nationally representative panel surveys on aging with the Health and Retirement Study or international studies that utilize a survey instrument that is harmonized with the Health and Retirement Study. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2011.

Synopsis

The sponsors provide support for research grant applications on fatigue and fatigability in aging. This FOA is intended to promote research studies employing transdisciplinary approaches that could lead to increased understanding of mechanisms contributing to, assessment of, or potential interventions for, increased fatigue or fatigability in older persons. Both animal models and humans are appropriate for study under this FOA. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after May 16, 2009. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2012.

Synopsis

The sponsor invites applications from institutions/organizations that propose to study decision-making processes in adolescents as they relate to drinking behavior, and the role of neural circuitry development in adolescent decision-making and alcohol abuse and dependence. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after May 16, 2009. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2012.

Synopsis

The sponsors invite applications from institutions/organizations that propose to study neurobiological and behavioral mechanisms contributing to concurrent alcohol and nicotine use and dependence. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after September 16, 2008. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2011.

Synopsis

The sponsor invites applications to support the secondary analysis of existing datasets with the goal of enhancing the understanding of the patterns of alcohol consumption and the epidemiology of alcohol-related problems. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after September 16, 2008. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2011.

Synopsis

The sponsor invites applications to support the secondary analysis of existing datasets with the goal of enhancing the understanding of the patterns of alcohol consumption and the epidemiology of alcohol-related problems. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on March 17, 2010.

Synopsis

The sponsor provides support for research on behavioral and pharmacological treatment for alcohol use disorders; organizational, financial, and management factors that facilitate or inhibit the delivery of services for alcohol use disorders; and phenomenon of recovery from alcohol use disorders. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on March 17, 2010.

Synopsis

The sponsor provides support for applications from institutions/organizations that propose to investigate the underlying molecular mechanisms of the development as well as reversal of alcohol-induced liver fibrosis. Liver fibrosis comprises excessive deposition of extracellular matrix (ECM) components, especially collagen, and activation of hepatic stellate cells (HSCs) is the primary event that triggers the process of fibrogenesis. Understanding the mechanisms of alcohol-induced liver fibrosis is important for the development of strategies for prevention and treatment of this condition. This FOA encourages applicants to test small molecules that reverse or prevent alcohol-induced liver fibrosis. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2010.

Synopsis

The sponsors provide support for Research Grant (R03) applications from institutions/organizations that propose to examine associations between nutrition and alcohol-related health outcomes in humans and animal models. The goal of this program announcement is to stimulate a broad range of research on the role of nutrition in the development, prevention, and treatment of a variety of alcohol-related health outcomes including alcohol dependence and psychiatric co-morbidities, chronic and acute diseases, and organ function and damage. Study designs may include biomedical research, epidemiologic approaches, and intervention studies. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2010.

Synopsis

The sponsors provide support for applications from institutions/organizations that propose to examine associations between nutrition and alcohol-related health outcomes in humans and animal models. The goal of this program announcement is to stimulate a broad range of research on the role of nutrition in the development, prevention, and treatment of a variety of alcohol-related health outcomes including alcohol dependence and psychiatric co-morbidities, chronic and acute diseases, and organ function and damage. Study designs may include biomedical research, epidemiologic approaches, and intervention studies. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on July 17, 2010.

Synopsis

The sponsor provides support for research grant applications on screening and brief interventions to prevent and/or reduce alcohol use and its adverse consequences. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on July 17, 2010.

Synopsis

The sponsor provides support for research grant applications on screening and brief interventions to prevent and/or reduce alcohol use and its adverse consequences. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2010.

Synopsis

The sponsor provides support for research on the effects of alcohol-related public policies on health-related behaviors and outcomes, evaluations and analyses of the effectiveness of public policy measures in improving public health and reducing the burden of alcohol-related illness and mortality, and research to advance methods and measurement used in studying relationships between alcohol-related public policies and health-related behaviors and outcomes. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2010 .

Synopsis

The sponsor provides support for research on the effects of alcohol-related public policies on health-related behaviors and outcomes, evaluations and analyses of the effectiveness of public policy measures in improving public health and reducing the burden of alcohol-related illness and mortality, and research to advance methods and measurement used in studying relationships between alcohol-related public policies and health-related behaviors and outcomes. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on February 17, 2011.

Synopsis

The sponsor provides support for research investigating the epidemiology of alcohol use and alcohol use disorders and the prevention of underage drinking, alcohol use disorders, and other alcohol-related harms. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.