Synopsis

The Office of Academic Exchange Programs of the Bureau of Educational and Cultural Affairs announces an open competition to administer the FY2010 Global Undergraduate Exchange Program for Pakistan. Public and private non-profit organizations meeting the provisions described in Internal Revenue Code section 26 USC 501(c)(3) in the United States may submit proposals to organize and carry out academic exchange activities for students from underrepresented sectors in Pakistan. The recipient organization will be responsible for the following aspects of the program: Placement of no less than 100 foreign students at accredited U.S. institutions (50 for fall semester 2010, 50 spring semester 2011) student travel to the U.S., orientation, enrichment programming, advising, monitoring and support, pre-return activities, evaluation, and follow-up with program alumni. Support for this program is being provided from special FY2009/FY2010 supplemental funds that have been appropriated to the Department. It is anticipated that the total amount of funding for FY2010 administrative and program costs will be $2,000,000 pending availability of funds.

Deadline Note

Proposals can be submitted from September 1, 2009 to October 1, 2009 and from January 15, 2010 to February 15, 2010.

Synopsis

The IMEE program focuses on the impact of large-scale hazards on civil infrastructure and society and on related issues of preparedness, response, mitigation, and recovery.

Deadline Note

Proposals will be accepted within a window of one month before the deadline date.

Synopsis

The CIS program supports research leading to the intelligent engineering of distributed infrastructure systems.

Deadline Note

Proposals are accepted within a window of one month before the deadline date.

Synopsis

The IMEE program focuses on the impact of large-scale hazards on civil infrastructure and society and on related issues of preparedness, response, mitigation, and recovery.

Deadline Note

Proposals will be accepted from September 1, 2009 to October 1, 2009 and January 15, 2010 - February 15, 2010.

Synopsis

The SSS program supports research on methods to acquire and use sensor data on civil, mechanical, and manufacturing systems.

Deadline Note

Proposals may be submitted from September 1, 2009 to October 1, 2009 and January 15, 2010 to February 15, 2010.

Synopsis

The NBM program supports fundamental research in biomechanics and nanomechanics.

Deadline Note

The window for submission of proposals is September 1, 2009 to October 1, 2009 and January 15, 2010 to February 15, 2010.

Synopsis

The OR program supports research leading to advances in the science of models and algorithms that are applicable to the operation and optimization of large-scale systems.

Deadline Note

The submission windows for proposals are between September 1, 2009 to October 1, 2009 and January 15, 2010 to February 15, 2010.

Synopsis

The MPM program supports fundamental research on the interrelationship of materials processing, structure, performance and process control.

Deadline Note

The window for submission of proposals is September 1, 2009 to October 1, 2009 and January 15, 2010 to February 15, 2010.

Synopsis

The NM program supports research and education on manufacturing at the nanoscale, and the transfer of research results in nanoscience and nanotechnology to industrial applications.

Deadline Note

The window for submission of proposals is September 1, 2009 to October 1, 2009 and January 15, 2010 to February 15, 2010.

Synopsis

The SMM program supports fundamental research on the behavior of civil infrastructure materials and the mechanics of structural components in the built environment.

Deadline Note

The window for submission of proposals is September 1, 2008 to October 1, 2008 and January 15, 2009 to February 15, 2009 .

Synopsis

The MES program supports research on design, planning, and control of operations in manufacturing enterprises.

Deadline Note

Proposals may be submitted from September 1, 2009 to October 1, 2009 and January 15, 2010 to February 15, 2010.

Synopsis

The EDI program supports research leading to design theory and to tools and methods that enable implementation of the principles of design theory in the practice of design across the full spectrum of engineered products.

Deadline Note

Proposals may be submitted from September 1, 2009 to October 1, 2009 and January 15, 2010 to February 15, 2010.

Synopsis

The MSE program supports fundamental research leading to a better understanding of the effect of microstructure, surfaces and coatings on the properties and performance of engineering materials, and the ultimate control of these properties through material design.

Deadline Note

Full proposals should be submitted from September 1, 2009 to October 1, 2009 and from January 15, 2010 - February 15, 2010.

Synopsis

The CS program supports innovative research on control theory and control technology driven by real life applications.

Deadline Note

Proposals may be submitted from September 1, 2009 to October 1, 2009 and January 15, 2010 to February 15, 2010.

Synopsis

The HMSE program supports fundamental research on the design and performance of structural systems and on new technologies for improving the behavior, safety, and reliability of structural systems and their resistance to natural hazards such as earthquakes and technological hazards (such as bombs).

Deadline Note

Proposals may be submitted from September 1, 2010 to October 1, 2010 and January 15, 2010 to February 15, 2010.

Synopsis

The MOM program supports fundamental research on solid mechanics including theoretical, analytical, and computational approaches, model-based simulation, and the development of constitutive models.

Deadline Note

Proposals can be submitted from September 1, 2009 to October 1, 2009 and January 15, 2010 to February 15, 2010.

Synopsis

The SES program supports research on strategic decision making, design, planning and operation of commercial, nonprofit, and institutional service enterprises with the goal of improving their overall effectiveness and cost reduction.

Deadline Note

Proposals can be submitted from September 1, 2009 to October 1, 2009 and January 15, 2010 to February 15, 2010.

Synopsis

The MCME program supports fundamental research leading to improved machines and applications for both manufacturing and construction.

Synopsis

Support is provided for participation and ocean drilling-related research performed by U.S. scientists.

Synopsis

Support is provided for research in biological oceanography.

Synopsis

Grants support research into the chemical components, reaction mechanisms, and geochemical pathways within the ocean and at its interfaces with the solid earth and the atmosphere.

Synopsis

Support is provided for research on a wide range of topics associated with the structure and movement of the ocean, with the way in which it transports various quantities, with the way the ocean's physical structure interacts with the biological and chemical processes within it, and with interactions between the ocean and the atmosphere, solid earth and ice that surround it.

Synopsis

Support is provided for research on all aspects of geology and geophysics of the ocean basins and margins, as well as the Great Lakes.

Deadline Note

Full proposal dates vary according to the program: Oceanographic Instrumentation - October 15, 2009; Ship Operations Program - November 1, 2009; Oceanographic Technical Services - November 15, 2009; Ocean Technology and Interdisciplinary Coordination - February 15, 2010. For the Ship Acquisition and Upgrade program and other Oceanographic Facility Activities, the program should be contacted directly.

Synopsis

The sponsor offers funding for construction, conversion, acquisition and operation of major shared-use oceanographic facilities.

Synopsis

The Oceanographic Technology and Interdisciplinary Coordination (OTIC) Program supports a broad range of research and technology development activities.

Deadline Note

The January 15 and August 15 target dates refer to regular proposals. The February 15 and October 15 target dates refer to dissertation proposals.

Synopsis

Support is provided for research in sociology.

Deadline Note

Regular Grants are targeted for January 15, 2010. Proposals for Doctoral Dissertation Research Improvement Awards (DDRI) are due by October 15, 2009 and February 15, 2010.

Synopsis

The Geography and Regional Science (GRS) Program sponsors research on the geographic distributions and interactions of human, physical, and biotic systems on the Earth's surface.

Deadline Note

Proposals for Doctoral Dissertation Enhancement Projects may be submitted at any time. Proposals for International Research Experiences for Students may be submitted by September 15, annually, for activities for the subsequent summer, or by February 15, annually, for activities at other times.

Synopsis

The Developing Global Scientists and Engineers program provides highest quality international research experiences for U.S. students.

Deadline Note

Optional letters of intent are due on February 15, 2010. Full applications are due on April 27, 2010.

Synopsis

The purpose of this project is to support state, major urban, and tribal public health agencies, national organizations and state coalitions to improve maternal, infant, child, and reproductive health through the application of evidence-based approaches. Additionally, as one of the goals of the Division of Reproductive Health is to promote partnerships at the local, state, tribal, and national levels, this project highlights the importance of engaging partners in the applied sciences process including analysis of relevant data, interpretation of results, and translation of findings to public health practice.

Deadline Note

The deadline for receipt of optional letters of intent is February 15, 2010. The deadline for receipt of full applications is March 15, 2010.

Synopsis

The sponsor invites applications for the competing continuation of the Pediatric Acute Liver Failure Study Group. This FOA will utilize the NIH Cooperative Agreement (U01) grant mechanism.

Deadline Note

The deadline for receipt of optional letters of intent is February 15, 2010. The deadline for receipt of full applications is March 15, 2010.

Synopsis

The sponsor invites applications for the competing continuation of the Adult Acute Liver Failure Study Group. This FOA will utilize the NIH Cooperative Agreement (U01) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after February 16, 2010. The deadline for receipt of optional letters of intent is February 16, 2010. The deadline for receipt of full applications is March 15, 2010.

Synopsis

The sponsor invites projects that address research endeavors in specific areas that will benefit from significant three-year funds without the expectation of continued NIH funding beyond this period. The research supported by the program should have high short-term impact, and a high likelihood of enabling growth and investment in biomedical research and development, public health, and health care delivery. Applicants may propose to address either a specific disease- or technology-related research question relevant to the mission of one or more participating Institutes and Centers, or propose the creation of a unique infrastructure/resource designed to accelerate scientific progress in the future. All NIH Institutes and Centers with funding authority will participate with the NIH Office of the Director in this initiative. This FOA will be administered by the Office of the Director of the NIH (http://www.nih.gov). Awards will be administered by the participating Institutes and Centers. This FOA will utilize the NIH RC4 award mechanism.

Deadline Note

This program will expire on May 8, 2010.

Synopsis

The sponsor offers support for Small Research Grant (R03) applications. The R03 grant mechanism supports different types of health services research projects including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and, development of new research technology.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after January 16, 2009. This program will expire on November 17, 2011.

Synopsis

The sponsor provides support for a wide variety of research designs in order to improve the quality, safety, effectiveness, and efficiency of health care through the implementation and use of health IT. These designs include: small pilot and feasibility or self-contained health IT research projects; secondary data analysis of health IT research; and economic (prospective or retrospective) analyses of health IT implementation and use. Through economic analyses estimates of health IT implementation and use costs and benefits will be generated. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after January 16, 2009. This program will expire on November 17, 2011.

Synopsis

The sponsor provides support for short-term preparatory, pilot or feasibility studies that will inform larger scale real world health IT implementation and use or the conduct of more comprehensive health IT implementation research. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Synopsis

The purpose of the Advanced Education Nursing (AEN) Program is to provide funding for projects to prepare advanced education nurses through the enhancement of advanced nursing education and practice.

Synopsis

The Fairbanks District Mine Hazard Inventory will apply technical archaeological methods to systematically identify and inventory abandoned mine land hazards within the BLM’s Fairbanks District. This work will begin with a Class I literature and data review to determine and prioritize survey blocks. This will be followed by Class II sample and Class III intensive surveys of select blocks and drainages. The project will result in a final report containing a detailed account of the areas surveyed, the hazards identified, and their association with cultural resources. This final report will also contain the historic context necessary to determine if identified, archaeological sites that are eligible for inclusion in the National Register of Historic Places. This work will generate geospatial data that will be inserted in BLM and State of Alaska AML and Cultural Resources databases. It is anticipated that this work will create one fulltime professional job for the duration of the project, and at least 4 seasonal technician level positions. This work will also help jumpstart the aviation industry by involving use of aircraft with this project. Of equal importance, this project will address important legacy issues related to mining that have been largely unattended to for decades.

Synopsis

The Bureau of Reclamation (Reclamation) manages 348 reservoirs in the 17 Western States. Reclamation also manages,(with partners), 289 recreation sites that have over 90 million visits annually. As required under Executive Order 12962 “Recreational Fisheries,” dated June 7, 1995, Reclamation is responsible for increasing public awareness of recreational opportunities at these reservoirs. Since 1992, Reclamation has provided support for fishing events that benefit disabled and disadvantaged children at its reservoirs. The previous contractors/recipients were organized to join professional sport fishing volunteers with disabled and disadvantaged children for a day of outdoor recreational fishing. These fishing events are designed to create an environment in which both children and volunteers will benefit by each one bringing to the event their own experiences and lessons to share. Because the scope of these proposed events will involve not just government entities but also volunteers from local communities, the recipient will need to seek other volunteer assistance to fulfill this purpose. This will also increase awareness of disabled and disadvantaged children in local communities.

Synopsis

The sponsor solicits competitive proposals from eligible organizations to enter into cooperative agreements to outreach to the small business community in their designated region and provide financial and technical assistance, business training programs, such as, business assessment, management training, counseling, technical assistance, marketing and outreach, and the dissemination of information, to encourage and assist small businesses to become better prepared to compete for, obtain, and manage sponsor funded transportation-related contracts and subcontracts at the federal, state and local levels.

Synopsis

The sponsor awards the National Award for Museum and Library Service, which honors outstanding American museums and libraries that have made extraordinary contributions to their communities. Any individual may submit a nomination.

Synopsis

The sponsor awards the National Medal for Museum and Library Service, which honors outstanding American libraries and museums that have made extraordinary contributions to their communities. Any individual may submit a nomination, and nominations of libraries of all sizes are encouraged.

Synopsis

This program provides grants for capital improvements, and related infrastructure improvements at qualified shipyards that will be effective in fostering efficiency, competitive operations, and quality ship construction, repair, and reconfiguration.

Deadline Note

The due date for Step 1 proposals is February 16, 2010. The sponsor will invite successful applicants from the Step 1 process to submit a Step 2 proposal, which will be due on April 20, 2010.

Synopsis

The sponsor solicits ground-based proposals for the Space Radiation Program Element (SRPE) components of the Human Research Program (HRP). Proposals are solicited by the SRPE in the area of Space Radiation Biology utilizing beams of high energy heavy ions simulating space radiation at the NASA Space Radiation Laboratory (NSRL), at Brookhaven National Laboratory (BNL) in Upton, New York.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after May 16, 2009. The deadlines for receipt of standard R01 applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2012.

Synopsis

The sponsor invites grant applications for studies that focus on research to define factors affecting energy balance and to define mechanisms influencing cancer risk, prognosis, and quality of life. These studies may range from new analyses of existing datasets to additional collection of data and biological specimens in ongoing investigations. It is anticipated that the knowledge gained will provide additional information to better understand the relationships among energy balance, cancer risk, and prognosis. This FOA will use the NIH Research Project (R01) award mechanism.

Deadline Note

The deadlines for receipt of standard R01 applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on January 8, 2012.

Synopsis

The sponsor invites applications for research projects that investigate the effects of Erythropoietin (EPO) on tumor cell growth. EPO has been widely used to relieve the anemia associated with renal failure. In addition, EPO and other erythropoiesis stimulating agents (ESAs) have recently been used to treat the anemia associated with cancer chemotherapy. However, several clinical trials involving administration of ESAs, have suggested that ESAs may accelerate tumor progression and increase mortality in cancer patients. It is therefore important to understand the biology of ESAs on tumor cell growth and apoptosis. The purpose of this FOA is to stimulate high quality research on the effects of ESAs on tumor cell biology and tumor progression. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after May 18, 2009. The deadlines for receipt of standard R21 applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2012.

Synopsis

The sponsors invite applications for basic, pre-clinical, and clinical complementary cancer research. The research should relate to the areas of prevention, diagnosis, and treatment of cancer as well as management of cancer symptoms and side effects due to conventional cancer treatment. In addition, this FOA encourages the development and application of emerging and innovative technologies, including identification of novel therapeutics in the pharmacopoeia of Traditional Medical Systems (as defined by the World Health Organization), use of complementary approaches to improve the therapeutic ratio of standard and investigational anti-cancer therapies, and research on lifestyle modifications (e.g. diet, exercise, mind-body approaches) for their impact on cancer outcomes (e.g., response to conventional cancer therapy, survival). The overarching goals of this FOA is to encourage investigators to submit high quality, preliminary research of humans that will advance the science of Complementary and Alternative Medicine (CAM) and provide a solid foundation and justification for future research project (R01) grant applications to definitively determine the efficacy of CAM approaches. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after May 18, 2009. The deadlines for receipt of standard R03 applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2012.

Synopsis

The sponsor invites applications for basic, pre-clinical, and clinical complementary cancer research. The research should relate to the areas of prevention, diagnosis, and treatment of cancer as well as management of cancer symptoms and side effects due to conventional cancer treatment. In addition, this FOA encourages the development and application of emerging and innovative technologies, including identification of novel therapeutics in the pharmacopoeia of Traditional Medical Systems (as defined by the World Health Organization), use of complementary approaches to improve the therapeutic ratio of standard and investigational anti-cancer therapies, and research on lifestyle modifications (e.g. diet, exercise, mind-body approaches) for their impact on cancer outcomes (e.g., response to conventional cancer therapy, survival). The overarching goals of this FOA is to encourage investigators to submit high quality, preliminary research of humans that will advance the science of Complementary and Alternative Medicine (CAM) and provide a solid foundation and justification for future research project (R01) grant applications to definitively determine the efficacy of CAM approaches. The R03 grant mechanism supports different types of projects including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. The R03 is intended to support small research projects that can be carried out in a short period of time with limited resources. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after September 16, 2009. The deadlines for receipt of standard R01 applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2012.

Synopsis

The sponsor invites research grant applications from institutions/organizations for the development and validation of biomarkers for: a) early detection, prediction of progression, and recurrence of hematopoietic malignancies, especially in high-risk individuals; and, b) for risk assessment of primary and secondary hematopoietic malignancies. This FOA is also encourages the development and improvement of specific technologies and methods for quantitative detection of novel biomarkers associated with hematopoietic malignancies. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after September 16, 2009. The deadlines for receipt of standard R01 applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2012.

Synopsis

The sponsor invites applications from institutions/organizations on the discovery and characterization of non-coding (nc) RNAs in preneoplasias and early stage cancers to: 1) improve early cancer detection, intervention, and prevention; 2) predict risk of progression from preneoplasia to cancer, and 3) distinguish benign lesions from precancerous lesions. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after May 16, 2009. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2012.

Synopsis

The sponsors invite the submission of applications in developmental and formative behavioral research in cancer prevention and control. This FOA will support innovative pilot projects or feasibility studies, which will facilitate the growth of research science in the cancer control continuum from a behavioral perspective. This FOA includes and incorporates the research interests of the Behavioral Research program, the Office of Cancer Survivorship, and the Community Oncology and Prevention Trials Research Group. This FOA is appropriate for testing timely interventions in pilot studies for feasibility or using rigorous qualitative research methods to assess the potential efficacy of an intervention. It is also appropriate for the psychometric evaluation of new measures or culturally appropriate ones to be adapted for use in populations where measures have not yet been developed or validated. This FOA encourages applications that include small cross-disciplinary teams of investigators who bring perspectives from the behavioral and social sciences, as well as other fields of public health. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after May 16, 2009. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2012.

Synopsis

The sponsor invites grant applications for research entailing the use of health claims data for cancer surveillance. Cancer surveillance may include assessment of patterns of care, quality, and outcomes of care, and health disparities across the continuum of treatment. The objective of this FOA is to encourage R03 grant applications from individuals who are interested in carrying out small research projects that are designed to expand our understanding of the validity of and methods needed to use claims data for cancer surveillance. Responses to this FOA may also include pilot analyses needed to provide preliminary data for larger grant proposals. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after May 16, 2009. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2012.

Synopsis

The sponsor invites grant applications for research entailing the use of health claims data for cancer surveillance. Cancer surveillance may include assessment of patterns of care, quality, and outcomes of care, and health disparities across the continuum of treatment. The objective of this Funding Opportunity Announcement (FOA) is to encourage R21 grant applications from individuals who are interested in carrying out exploratory/ developmental research projects that are designed to expand our understanding of the validity of and methods needed to use claims data for cancer surveillance. Responses to this FOA may also include pilot analyses needed to provide preliminary data for larger grant proposals. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after September 16, 2009. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2012.

Synopsis

The sponsors invite applications for clinical and preclinical research to determine how diet and dietary factors, including dietary supplements, impact DNA methylation, histone posttranslational modification, noncoding RNA, and other epigenetic processes involved in cancer prevention and development. Another important aim of this FOA is to encourage collaborations between nutrition and epigenetic experts to study bioactive food components with cancer-preventative properties and to examine key epigenetic events in cancer processes (e.g., carcinogen metabolism, cell division, differentiation, and apoptosis) in order to begin to establish linkages between epigenetics, methylation patterns, and tumor incidences/behaviors. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after January 16, 2010. The deadlines for receipt of standard R01 applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on January 8, 2013.

Synopsis

The sponsors invite applications that propose to: (1) conduct evaluation research on obesity-related “natural experiments” (defined here as community and other population-level public policy interventions that may affect diet and physical activity behavior), and/or (2) develop and/or validate relevant community-level measures (instruments and methodologies to assess the food and physical activity environments at the community level). The overarching goal of this FOA is to inform public policy and research relevant to (1) diet and physical activity behavior, and (2) weight and health outcomes of Americans. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after January 16, 2010. The deadlines for receipt of standard R01 applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on January 8, 2013.

Synopsis

The sponsors invite applications that propose to: (1) conduct evaluation research on obesity-related “natural experiments” (defined here as community and other population-level public policy interventions that may affect diet and physical activity behavior), and/or (2) develop and/or validate relevant community-level measures (instruments and methodologies to assess the food and physical activity environments at the community level). The overarching goal of this FOA is to inform public policy and research relevant to (1) diet and physical activity behavior, and (2) weight and health outcomes of Americans. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after January 16, 2010. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on January 8, 2013.

Synopsis

The sponsor invites research applications that propose to evaluate profiles of methylation, histone modifications and micro RNA (miRNA) and their association with risk of developing cancer in different populations. The overarching goal of this FOA is to provide support for population based studies to define the role of epigenetic markers (methylation, histone and micro RNA profiles) changes to understand cancer etiology. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after January 16, 2010. The deadlines for receipt of standard R01 applications under this announcement are: February 16, June 16 and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on January 8, 2013.

Synopsis

The sponsors invite applications that propose to: (1) foster multidisciplinary research that will evaluate how policies (federal, state and school district levels) can influence school physical activity and nutrition environments, youths’ obesogenic behaviors (e.g., nutrition and physical activity behaviors), and weight outcomes; (2) understand how schools are implementing these policies and examine multi-level influences on adoption and implementation at various levels (e.g., federal, state, school district, and school); and (3) understand the synergistic or counteractive effect of school nutrition and physical activity polices on the home and community environment and body weight. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after January 16, 2010. The deadlines for receipt of standard R01 applications under this announcement are: February 16, June 16 and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on January 8, 2013.

Synopsis

The sponsors invite applications that propose to: (1) foster multidisciplinary research that will evaluate how policies (federal, state and school district levels) can influence school physical activity and nutrition environments, youths’ obesogenic behaviors (e.g., nutrition and physical activity behaviors), and weight outcomes; (2) understand how schools are implementing these policies and examine multi-level influences on adoption and implementation at various levels (e.g., federal, state, school district, and school); and (3) understand the synergistic or counteractive effect of school nutrition and physical activity polices on the home and community environment and body weight. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

This program will expire on September 8, 2012.

Synopsis

The sponsor provides support for the development of novel technologies for capturing, enriching, and preserving exfoliated abnormal cells from body fluids or effusions as well as methods for concentrating the tumor-derived sub-cellular material for use in biomarker studies. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after May 16, 2009. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2012.

Synopsis

The sponsor invites research applications from institutions and organizations to evaluate the utility and pilot the application of new strategies for determining prognosis or predicting response to therapy for cancer. The purpose of this FOA is to develop newly discovered biomarkers from initial correlative observations into assays or test systems suitable for use in clinical trials or other types of confirmatory clinical research studies. This program will provide tools whose purpose is to improve clinical decision-making in the care of cancer patients. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2011.

Synopsis

The sponsor offers support for research to: improve the measurement of racial /ethnic discrimination in health care delivery systems through improved instrumentation, data collection and statistical/analytical techniques; enhance understanding of the influence of racial/ethnic discrimination in health care delivery and its association with disparities in disease incidence, treatment and outcomes among disadvantaged racial/ethnic minority groups; and reduce the prevalence of racial/ethnic health disparities through the development of interventions to reduce the influence of racial/ethnic discrimination on health care delivery systems in the United States. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

This program will expire on September 8, 2011.

Synopsis

The sponsors offer support for individual-investigators or small groups to collaborate with the NIH Roadmap for Medical Research National Centers for Biomedical Computing (NCBCs). The intention of the collaborating projects is to engage researchers across the nation in building an excellent biomedical computing environment, using the computational tools and biological and behavioral application drivers of the funded NCBCs as foundation stones. This FOA is intended to support exploratory biomedical informatics and computational biology research—applications should be innovative, with high risk/high impact in new areas that are lacking preliminary data or development. This program will use the NIH Exploratory/Developmental (R21) grant mechanism. This PAR is developed as a Roadmap affiliated initiative.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after May 16, 2008. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2011.

Synopsis

The sponsor offers support for research that will enhance the understanding of the relationship between exposures to bioactive food components and/or environmental chemicals in utero , hormonal and growth factor response, gene expression or epigenetic changes and subsequent mammary cancer risk in preclinical models. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after January 16, 2009. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on January 8, 2012. Electronic application submission is required for this FOA. The new Adobe versions of the application forms are not yet available. Please check back in December to download the application package.

Synopsis

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after May 16, 2008. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2011.

Synopsis

The sponsor offers support the research on all aspects of stem cell biology, including research into the molecular and biochemical regulation of embryonic and adult stem cell behavior, with the goal of ultimately improving the specificity and long-term effectiveness of cancer therapy, through the targeting of those cells most responsible for disease progression and metastasis. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on November 6, 2011.

Synopsis

The sponsor offers support for projects that enhance the state-of-the-science on the causes of obesity and to inform Federal decision making on effective public health interventions for reducing the rate of obesity in the United States. This FOA is also intended to promote collaborative activities between researchers trained in economics and researchers specializing in public health, cancer, cardiovascular diseases, and other chronic diseases so that the desired goals can be more efficiently, quickly, and successfully attained. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2011.

Synopsis

The sponsor provides support for translational correlative studies that utilize annotated tumor and/or other biospecimens collected during large-scale multi-institutional clinical and/or prevention trials, respectively, with a goal to facilitate predictions of responses to current interventions, and inspire future development of improved therapeutic and preventive strategies. Projects proposed in response to this FOA should address the correlations between intervention outcomes and cancer patients’ disease characteristics determined at various cellular/molecular levels. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after May 16, 2008. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2011.

Synopsis

The sponsor offers support for research proposals focused on identifying protein biomarkers for cancers where etiology of the disease is attributed to infectious agents. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

This program will expire on January 8, 2011.

Synopsis

The sponsor offers support for research projects that will enhance understanding of human decision-making processes so that individuals can make more informed and satisfying choices regarding their health. The NCI encourages collaborations between basic judgment and decision-making researchers, and applied cancer control researchers that will elucidate single-event decision-making processes at the level of the individual patient or health care provider that are pertinent to cancer prevention, detection, treatment, survivorship, or end-of-life care. For the purpose of this initiative, a single-event decision is defined as a discrete decision made at a specific point in time. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after February 5, 2008. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2011.

Synopsis

The sponsor offers support for research to: improve the measurement of racial /ethnic discrimination in health care delivery systems through improved instrumentation, data collection and statistical/analytical techniques; enhance understanding of the influence of racial/ethnic discrimination in health care delivery and its association with disparities in disease incidence, treatment and outcomes among disadvantaged racial/ethnic minority groups; and reduce the prevalence of racial/ethnic health disparities through the development of interventions to reduce the influence of racial/ethnic discrimination on health care delivery systems in the United States. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on January 8, 2011.

Synopsis

The sponsors offer support for research to critically evaluate the use of exfoliated cells to monitor the physiological effects of dietary bioactive food components thought to be involved with cancer prevention. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after May 16, 2009. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on March 6, 2009.

Synopsis

The sponsors applications that propose multidisciplinary research on potential reduced-exposure tobacco products, both smoked and smokeless. The multidisciplinary studies can span basic, biological, behavioral, surveillance, and epidemiology research. The tobacco industry is currently promoting several new products with claims that they: a) are less either harmful or less addictive; and b) purportedly deliver lower amounts of toxic, carcinogenic, and/or addictive agents to the user compared with conventional products. However, to date, the scientific evidence is insufficient to evaluate whether these new products actually reduce the users’ exposure or risk for tobacco-related diseases. The overarching goal of this FOA is to determine whether potential reduced-exposure tobacco products provide a truly, less-harmful alternative to conventional tobacco products, both at the individual and population level. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2009.

Synopsis

The sponsors offers support for Exploratory/Developmental Research Grant applications (R21) to investigate ethical issues in human subjects research. The purpose of this funding opportunity announcement is to solicit research addressing the ethical challenges of human subjects research in order to optimize the protection of human subjects and enhance the ethical conduct of human subjects research.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 2, May 1, and September 1 annually. This program will expire on September 8, 2010.

Synopsis

The sponsors offers support for research grant applications to investigate ethical issues in human subjects research. The purpose of this funding opportunity announcement is to solicit research addressing the ethical challenges of human subjects research in order to optimize the protection of human subjects and enhance the ethical conduct of human subjects research. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after May 16, 2009. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2012.

Synopsis

The sponsor invites research applications from institutions and organizations to evaluate the utility and pilot the application of new strategies for determining prognosis or predicting response to therapy for cancer. The purpose of this FOA is to develop biomarkers from initial correlative observations into assays or test systems suitable for use in clinical trials or other types of confirmatory clinical research studies. This program will provide tools whose purpose is to improve clinical decision-making in the care of cancer patients. This FOA will use the NIH Exploratory/Developmental Phase II Research Grant (R33) mechanism.

Deadline Note

This program will expire on January 8, 2011.

Synopsis

The sponsors offers support aimed at enhancing nanoscience and nanotechnology research focused on problems in biology and medicine. Nanoscience and nanotechnology refer to research and development on the understanding and control of matter at a length scale of approximately 1 - 100 nanometers, where novel properties and functions occur because of the size. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after January 16, 2010. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on January 8, 2013.

Synopsis

The sponsor invites research applications from clinicians, epidemiologists, geneticists, statisticians, and translational researchers working in the field of cancer control and prevention to improve existing models for cancer risk and prognosis by developing innovative research projects that use existing data; develop new models for cancer risk and prognosis; and validate new models and evaluate their utility in research and clinic settings. To explore this opportunity, the NCI Division of Cancer Control and Population Sciences (DCCPS) and the Division of Cancer Treatment and Diagnosis (DCTD) encourage applications for research projects to develop, apply, and evaluate new and existing cancer risk and prognostic prediction models for use by researchers, clinicians, and the general public. This FOA is designed to provide a mechanism of support for investigators to address two major challenges in model development, which are: integrating diverse types of data (e.g., clinical, demographic, pathologic, environmental, epidemiologic, outcomes, and genetic data from varied data marts or warehouses); and ensuring adequate validation (i.e., using multiple separate populations to define sensitivity, specificity, and positive and negative predictive values). This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

This program will expire on March 17, 2010.

Synopsis

The sponsors provide support for exploratory/developmental nutrition and cancer prevention research. Specifically, this initiative seeks to promote cancer prevention research to identify and characterize molecular targets for bioactive food components. A bioactive food component is defined as a dietary constituent that has a health benefit by altering one or more cellular processes when provided in quantities over and beyond that needed for basic nutrition. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2011.

Synopsis

The sponsor provides support for research efforts aimed at establishing the physiological significance of dietary components in modulating the tumoricidal cell activity of natural killer (NK) cells for cancer prevention. The focus of research projects proposed in response to this FOA should be on defining the minimum quantity and duration of exposure to specific dietary components to modulate tumoricidal cell activity of NK cells for cancer prevention and the underlying mechanism(s) accounting for this response. Proposed projects must include animal and/or human investigations to be considered responsive to this announcement. Highly purified populations of immune cells, specific tumor cells such as RMA-S that lack class I MHC expression, target cell-free system, or single-cell assays may be used to define the molecular basis for the diet-induced changes in tumoricidal activity. However, the in vitro studies are only to be used to support in vivo studies and should not constitute the primary focus of the application. Molecular targets for food components may be examined at the sites of the tumoricidal cell receptors and cancer cell specific ligands, the output of tumoricidal cytokines (e.g., IFN-g), and the release of lytic granules such as a granulysin, perforin, and serine proteases (granzymes). This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

The deadlines for receipt of standard R21 applications under this announcement are: June 16, October 16, and February 16 annually. The deadlines for AIDS and AIDS-related applications are: May 7, September 7, and January 7 annually. This program will expire on May 8, 2011.

Synopsis

The purpose of the sponsor's program is to stimulate the development and validation of novel mitochondrial (mt) DNA biomarkers for early detection, diagnosis, prognosis, and risk assessment of cancer. This FOA will stimulate research on mutations in mtDNA for identification of additional indicators of tumor development and progression, including mitochondrial somatic mutations and mitochondrial haplogroups. This program will use the NIH Research Project (R21) award mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2011.

Synopsis

The sponsors provide support for hypothesis-driven projects exploring associations between the built environment, other contextual features of where people of all ages live and work and health behaviors related to energy balance. These projects should use population level data from health surveys and other large health studies. It is expected that the proposed projects will be designed to add/include contextual variables at diverse levels of geographic aggregation to such studies on behaviors that affect individual energy balance and thereby health. Subsequent analyses should be aimed at understanding the relative importance of the contextual variables (including home, work, school, and/or other environments) as determinants of energy balance-related health behaviors. Grant applications will be expected to use population level data from diverse sources for: 1) generation and addition of new geographic information system (GIS) data layers for analysis of contextual variables such as measures of the built and natural environments, to existing studies; 2) analyses of existing confidential geographic-based data either on site, at survey data centers, or other protected sites; and/or 3) merging multiple health-related data resources to allow new analyses of associations between contextual variables and energy balance-related health behaviors. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2011.

Synopsis

The sponsor provides support for innovative research across multiple disciplines for a better understanding of the biology, etiology, detection, prevention, and treatment of pancreatic cancer. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2011.

Synopsis

The sponsor provides support for innovative research across multiple disciplines for a better understanding of the biology, etiology, detection, prevention, and treatment of pancreatic cancer. This program will use the NIH Small Research Grant (R03) award mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2011.

Synopsis

The sponsor provides support for research projects focused on the identification and characterization of diet-induced changes in inflammation linked to colon cancer risks. This FOA is designed to stimulate research efforts that will lead to the identification and characterization of: diet-induced changes in anti- and pro-inflammatory mediators that modulate colon cancer risk; b) genetic polymorphisms that modify the responses to specific bioactive food components with regard to colon cancer inhibition; and c) the physiological effectiveness of dietary components in terms of concentration, activity, duration of exposure, degrees of stability, chemical forms, and receptor-binding affinity in inflammatory colonocytes. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after September 16, 2008. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 16, 2011.

Synopsis

The sponsors provide support for research projects focused on the development and implementation of effective communication strategies related to diet and health. Specifically, this FOA is designed to promote interdisciplinary research, conducted at multiple levels (e.g., individual, community/environment, and policy) and across diverse populations, to evaluate effective communication approaches for changing dietary behaviors. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after September 16, 2008. The deadlines for receipt of standard R01 applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2011.

Synopsis

The sponsors provide support for grant applications that: (a) address the etiology and etiologic mechanisms of hepatocellular carcinoma (HCC); (b) propose development of animal models for HCC; (c) propose novel approaches to prevent HCC malignancy; (d) propose therapeutic or diagnostic tools for reliable prognostic indicators for HCC; and/or (e) develop therapeutic approaches to minimize morbidity and mortality associated with HCC in humans. The primary focus of the proposed project must be on the basic biology, prevention, and/or treatment of liver cancer. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after January 16, 2009. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2012.

Synopsis

The sponsor provides support for applications from institutions and organizations that are interested in developing and testing innovative methods in cancer detection, diagnosis, and prognosis. The NCI is especially interested in research studies that focus on the development and testing of improved methods for detecting specific characteristics of cancer, which can be subsequently used for the clinical management of cancer patients or individuals who are at risk for (developing) cancer. It is important that research studies focus on the search for molecular and cellular differences between tumors, pre-malignant, or normal tissues. The studies should determine the clinical translational significance of these differences by correlation with clinical parameters, in order to answer clinical problems related to detection, diagnosis, treatment, and prognosis. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2010.

Synopsis

The sponsor solicits applications from organizations proposing to develop, characterize or improve animal models for human disease or to improve diagnosis and control diseases of laboratory animals that may interfere with research. Models to be considered must be applicable to the research interests of two or more categorical NIH Institutes/Centers. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after January 16, 2010. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on January 8, 2013.

Synopsis

The sponsor invites applications for large-scale clinical vision research projects, including randomized clinical trials and epidemiologic studies. At the time of submission, applications requesting support for these activities are expected to provide detailed information regarding the study’s rationale, design, analytic techniques, protocols and procedures, facilities and environment, organizational structure, and collaborative arrangements. This information is best conveyed in a well-documented Manual of Procedures (MOP), the development of which represents a costly and time-consuming activity. The Clinical Study Planning Grant is designed to facilitate activities central to the refinement of a study’s protocol and procedures and the development of a detailed MOP. The NEI Clinical Study Planning Grant may be used to support the development of a MOP, as well as to conduct preliminary studies to refine study procedures and/or assess recruitment potential. The Clinical Study Planning Grant is applicable to both epidemiologic and clinical trial research studies. This FOA will utilize the Clinical Study Planning Grant Program for Clinical Trials (R34) mechanism.

Deadline Note

Applications may be submitted to Grants.gov in response to this announcement on or after September 16, 2009. The deadlines for receipt of standard applications under this announcement are: February 16, June 16, and October 16 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on September 8, 2012.

Synopsis

The sponsor invites applications from institutions/organizations that propose to conduct secondary data analyses utilizing existing database resources. Applications may be related to, but must be distinct from, the specific aims of the original data collection. The NEI supports an extensive portfolio of clinical trials and large-scale epidemiologic research projects, wherein numerous data collection activities are required to meet each project’s specific aims. The resultant wealth of data generated by these studies often provides unique, cost-effective opportunities to investigate additional research questions or develop new analytical approaches secondary to a project’s originally intended purpose. Data are not limited to that collected under NEI support but these data are of highest programmatic interest. The R21 may be used to develop new statistical methodologies or to test hypotheses using existing data. Applicants should consider the relevance of their proposed analyses to NEI programs and priorities as described in the “National Plan for Eye and Vision Research” available at http://www.nei.nih.gov. This program will use the NIH Exploratory/Developmental (R21) grant mechanism.