CHEM-CHEMISTRY -- 2000-01 Catalog
Chemistry & Biochemistry Department

Introductory course in chemistry. Measurement, metric system, properties of matter, chemical symbols, atomic structure, chemical formulas, nomenclature, chemical equations, the mole concept, stoichiometry. Not open to students who have credit in a college chemistry course. 3 lectures.

Fundamentals of chemical cause and effect - structure/ function relationships. Basic principles of chemistry and their applications to solving human problems in organic materials science, biochemistry, toxicology, environmental science, agriculture, nutrition, and medicine. 3 lectures, 1 laboratory. Prerequisite: Must satisfy ELM requirement.

Introduction to atomic theory, chemical reactions, bonding, stoichiometry, nomenclature, and solutions. Intended for students who are preparing for CHEM 212. 4 lectures, 1 laboratory. Prerequisite: CHEM 106 or equivalent, intermediate algebra, appropriate score on ELM. Not open to students with credit for CHEM 128.

General chemistry concepts presented using a materials science approach with engineering applications. Thermochemistry, atomic theory, bonding, solid state structures, fundamentals of organic chemistry including polymers. Laboratory work is closely coordinated with theory; computers integrated into the curriculum for data collection as well as multimedia work and tutorials. Guided inquiry and collaborative methods are emphasized. Not open to students with credit for CHEM 111 or CHEM 127. 3 lectures, 1 laboratory. Prerequisite: Intermediate algebra or MATH 104; and high school chemistry, CHEM 106 or equivalent.

A continuation of general chemistry designed for engineering students. Topics include solution chemistry, thermodynamics, kinetics, equilibrium, acids and bases, electrochemistry, and nuclear chemistry. Integration of laboratory with theoretical concepts. Use of computers for data acquisition and multimedia resources. Guided inquiry and collaborative methods emphasized. Not open to students with credit for CHEM 128. 3 lectures, 1 laboratory. Prerequisite: CHEM 124.

Introduction to atomic theory, chemical reactions, bonding, stoichiometry, nomenclature, gas laws, colligative properties, colloids, and solutions. Intended primarily for students whose majors are in the College of Science and Mathematics. Not open to students with credit in CHEM 111 or CHEM 124. 3 lectures, 1 laboratory. Prerequisite: Intermediate algebra or MATH 104; and high school chemistry, CHEM 106 or equivalent.

Continuation of CHEM 127. Oxidation-reduction reactions, electrochemistry, kinetics, equilibria, thermodynamics, acids and bases. Intended primarily for students whose majors are in the College of Science and Mathematics. Not open to students with credit in CHEM 125. 3 lectures, 1 laboratory. Prerequisite: CHEM 127.

Acid and base equilibria, buffers, transition elements, solubility, complex ions, hybridization, nuclear chemistry. Laboratory study of the chemical properties and semi-micro qualitative analysis of the representative group elements of the periodic table. Intended primarily for students whose majors are in the College of Science and Mathematics. 3 lectures, 1 laboratory. Prerequisite: CHEM 125 or CHEM 128.

Additional laboratory to be taken with CHEM 129. Includes chemical properties and semi-micro qualitative analysis of the transition and post-transition metal ions of the periodic table, methods of inorganic synthesis. 1 laboratory. Prerequisite: CHEM 111, CHEM 125, or CHEM 128.

Individual investigation, research, studies, or surveys of selected problems. Total credit limited to 4 units, with a maximum of 2 units per quarter. Prerequisite: CHEM 111, CHEM 124, or CHEM 127 and consent of department head.

Structure, isomerism, nomenclature, fundamental reactions of major functional groups and applications of organic chemicals in agriculture, medicine, industry, and the home. Not open to students with credit in CHEM 216. 4 lectures, 1 laboratory. Prerequisite: CHEM 111, or CHEM 128, or equivalent.

Structure, bonding, nomenclature, isomerism, stereochemistry and physical properties of organic compounds. Introduction to spectroscopy. Reactions and mechanisms of alkanes, alkenes, alkynes, cycloalkanes and aromatic compounds. Laboratory techniques in organic preparations. 4 lectures, 1 laboratory. Prerequisite: CHEM 111 or CHEM 125 or CHEM 128.

Reactions and reaction mechanisms of organic halides, alcohols, phenols, epoxides, ethers, carboxylic acids and their derivatives, aldehydes, ketones; acidity and basicity; infrared and NMR spectroscopy. 3 lectures, 2 laboratories. Prerequisite: CHEM 216.

Chemistry of amines, aromatic compounds, heterocycles, macromolecules, some biomolecules, carbanions, rearrangement and ultraviolet and mass spectrometry. 3 lectures. Prerequisite: CHEM 217.

Theory and application of chemical equilibrium to analytical problems. Survey of important analytical methods with stress placed on the theory and application associated with titrimetric and spectrophotometric analysis. 3 lectures, 2 laboratories. Prerequisite: CHEM 129.

Techniques of glassblowing applied to the making of simple laboratory apparatus. 1 laboratory. Prerequisite: CHEM 111, CHEM 124 or CHEM 127.

Fundamentals and applications of chemical thermodynamics of particular interest to engineers. Chemical and phase equilibria. 3 lectures. Prerequisite: PHYS 123 or PHYS 133, CHEM 125 or CHEM 129, MATH 143.

Applications of chemical thermodynamics. Electrochemistry. Kinetic theory of gases. Chemical kinetics. 3 lectures. Prerequisite: CHEM 305, or CHEM 351 or ME 302.

Chemistry of biomolecules including carbohydrates, proteins, fats, vitamins, enzymes and hormones. Basic molecular biology with applications to biotechnology and genetic engineering. Practical intermediary metabolism of prokaryotic and eukaryotic systems. 4 lectures, 1 laboratory. Prerequisite: CHEM 212 or equivalent.

Practice in multiple step organic synthesis, column chromatography, vacuum distillation, enzymes as chemical reagents, inert atmosphere techniques, introduction to FT NMR spectroscopy and mass spectrometry. 2 laboratories. Prerequisite: Concurrent or prior enrollment in CHEM 218.

Theory and analytical techniques associated with gravimetric analysis and titrimetric precipitimetry. Continuation of redoximetry. Introduction to instrumental methods of analysis, with theory and application of electrogravimetry, potentiometry and spectrophotometry. 2 lectures, 1 laboratory. Prerequisite: CHEM 231.

Basic principles of physiological chemistry including clinical significance of medical laboratory data. Introduction to the clinical aspects of carbohydrate, lipid and protein metabolism. 2 lectures. Prerequisite: CHEM 313 or CHEM 371; CHEM 231 recommended.

Medical laboratory techniques in analysis of serum, blood and urine for glucose, protein and lipids. Basic principles of physiological chemistry including clinical significance of medical laboratory data. Credit/No Credit grading only. 1 laboratory. Corequisite: CHEM 337. Prerequisite: CHEM 313 or CHEM 371. CHEM 231 strongly recommended.

Chemical aspects of water and water pollution: alkalinity; acid deposition, particularly relating to lake and stream acidification and forest decline; drinking water treatment and THMs; wastewater treatment; detergents, builders, and eutrophication; pesticides; other toxic organic compounds such as PCBs and dioxin; hazardous wastes; toxic elements such as Pb, Hg, Sn, Cd, and Se. 3 lectures. Prerequisite: CHEM 129 and CHEM 212 or CHEM 216.

Chemical aspects of the atmosphere and air pollution: greenhouse effect and global climate change; CFCs, the ozone layer, and the ozone hole; carbon monoxide, nitrogen oxides, and photochemical smog, particulate matter; radon, asbestos, indoor air pollution; sulfur oxides and acid deposition, particularly relating to atmospheric reactions and control options. 3 lectures. Prerequisite: CHEM 129 and CHEM 212 or CHEM 216.

Applicability of modern chemical instrumentation to the solution of present-day environmental problems. Includes instruction in operation of instrumentation, calculations, and interpretation of results from environmental analyses of a variety of air, water, and solid samples. 1 laboratory. Prerequisite: CHEM 341 or CHEM 342.

Laboratory regulations, equipment hazard analysis, hazardous chemicals, classification of chemicals, toxic materials handling, reaction hazards, radiation, emergency procedures, safety management programs and legal concerns. Includes project. 1 lecture. Prerequisite: CHEM 212 or equivalent.

Basic physical chemistry for the study of chemical and biochemical systems. Kinetic-molecular theory, gas laws, principles of thermodynamics. Not open to students with credit in CHEM 305. 3 lectures. Prerequisite: CHEM 129, PHYS 123 or PHYS 133; MATH 143.

Application of physical chemistry to chemical and biochemical systems. Electrochemistry, kinetics, viscosity, surface and transport properties. Not open to students with credit in CHEM 306. 3 lectures. Prerequisite: CHEM 305 or CHEM 351.

Principles and applications of quantum chemistry. Chemical bonding and molecular structure. Spectroscopy and diffraction. 3 lectures. Prerequisite: CHEM 352, or CHEM 306, or consent of instructor.

Experimental studies of gases, solutions, thermochemistry, chemical and phase equilibria, electrochemistry, chemical and enzyme kinetics, computational methods and applications to chemistry and biochemistry. 2 laboratories. Prerequisite: CHEM 231 and CHEM 306 or CHEM 352.

Experimental and computational investigations of quantum chemistry, spectroscopy, symmetry and statistical chemistry. 1 laboratory. Corequisite: CHEM 353.

Information searches in primary and secondary chemical literature and computer database. Organizing and presenting chemical information in written documents. 1 lecture, 1 activity. Prerequisite: CHEM 216 or CHEM 212.

Chemical and physical factors in biological processes. Chemistry and function of major cellular constituents: proteins, lipids, carbohydrates. 4 lectures, 1 laboratory. Prerequisite: CHEM 212 or CHEM 217. Recommended: CHEM 231.

Intermediary metabolism, regulation and integration of metabolic pathways, bioenergetics, photosynthesis, electron transport, nitrogen fixation, biochemical function of vitamins and minerals. 3 lectures. Prerequisite: CHEM 371.

Structure of nucleic acids and chromosomes. Mechanisms and regulation of nucleic acid and protein synthesis. Molecular biology techniques and protein targeting. 3 lectures. Prerequisite: CHEM 371.

Experiments in microbial metabolism, purification, analysis and manipulation of proteins and nucleic acids. 2 laboratories. Prerequisite: CHEM 371.

Introduction to techniques used in molecular biology and biotechnology; plasmid DNA extraction, characterization and use in transformation. Gene cloning, southern blotting, reverse transcription, and polymerase chain reaction. 2 laboratories. Prerequisite: MCRO 221 or MCRO 224, and BIO 351 or CHEM 373.

Introduction to pharmacology: history, sources, development and testing, physical and chemical properties, biochemical and physiological effects, mechanisms of action, and the therapeutic uses and toxicology of common drugs and poisons acting on the nervous, cardiovascular, immune and hormone systems, and on cancer, infectious disease, etc. Especially applicable to students in nonbiochemical disciplines. 3 lectures. Prerequisite: CHEM 313 or CHEM 371 or consent of instructor.

Application of chemical principles to terrestrial and extraterrestrial systems. Formation of the elements; chemical influences on the earth's formation; chemical evolution studies; age-dating techniques; reactions in sea water; petroleum and ore formation; distribution and movement of the elements. 3 lectures. Prerequisite: CHEM 216, CHEM 231.

Individual investigation, research, studies, or surveys of selected problems. Total credit limited to 4 units, with a maximum of 3 units per quarter. Prerequisite: Junior standing and consent of department head.

Selected advanced topics in physical chemistry, which may include statistical mechanics, computational chemistry, nonequilibrium thermodynamics, lasers in chemistry, solid-state and/or advanced spectroscopy. Total credit limited to 6 units. 3 lectures. Prerequisite: CHEM 353 or consent of instructor.

Methods of investigating reaction mechanisms, mechanisms of chemical catalysis, organic models of enzymes, chemistry of vitamins that serve as enzyme cofactors, chemistry of the phosphate group, synthesis of biomolecules. 3 lectures. Prerequisite: CHEM 218.

Modern methods of organic synthesis. Carbon-carbon bond forming reactions, functional group transformations, protecting groups, strategies of total synthesis of natural products. 3 seminars. Prerequisite: CHEM 218.

Advanced principles of physiologic chemistry including clinical significance of medical laboratory data. Theoretical and practical aspects of biochemical profiling. Theory of biochemical techniques in clinical chemistry and pathology, metabolic and organ-specific investigations and interpretation of results, clinical instrumentation, serum enzyme and hormone assay techniques. 3 lectures. Prerequisite: CHEM 337 or CHEM 372.

Theory and practice of biochemical techniques in clinical chemistry and pathology. Overview of clinical instrumentation. Credit/No Credit grading only. 1 laboratory. Prerequisite: CHEM 338 or CHEM 372; corequisite: CHEM 437.

Theory, practice and method selection of modern instrumental analytical techniques, including spectroscopic, electrochemical, chromatographic and thermal methods. Current industrial applications. Laboratory work emphasizes optimization of experimental parameters. 3 lectures, 2 laboratories. Prerequisite: CHEM 231, CHEM 354. Recommended: CHEM 353.

Physical properties of polymers and coatings and their measurement. Molecular weight averages, glass transition, thermodynamics of polymers. Viscoelastic properties, rheology, molecular weight determination. Thermal analysis, spectroscopic analysis, mechanical testing. 3 lectures. Prerequisite: CHEM 217.

Introduction to polymerization methods and mechanisms. Chemistry of initiators, catalysts and inhibitors. Uses of representative polymer types. Synthesis, film formation, structure and properties of polymers commonly used in coatings and adhesives. 3 lectures. Prerequisite: CHEM 217.

Surface energy. Capillarity, solid and liquid interface, adsorption. Surface areas of solids. Contact angles and wetting. Friction, lubrication and adhesion. Relationship of surface to bulk properties of materials. Applications. 3 lectures. Prerequisite: CHEM 305 or CHEM 351 or course in engineering thermodynamics.

Synthesis and characterization of polymers. Experimental techniques of step growth and chain growth polymerization. Experimental methods of molecular weight determination. Experimental methods of thermal, spectroscopic, and mechanical analysis. 2 laboratories. Prerequisite: CHEM 444. Recommended: CHEM 445 or concurrent.

Experimental techniques of producing and characterizing coatings. Compounding and formulating modern protective coatings. Modern methods of testing protective coatings. Surface preparation techniques. 2 laboratories. Prerequisite: CHEM 444, CHEM 445.

Selected students will spend up to 12 weeks with an approved polymers and coatings firm engaged in production or related business. Time will be spent applying and developing production and technical skills and abilities in the polymers and coatings industry. Prerequisite: CHEM 217 or consent of instructor.

History, development, and use of chemical weapons. Chemical disarmament. Production and destruction of modern agents. Use of chemical agents in Southeast Asia and Middle East. Ethics of chemical warfare. 2 seminars. Prerequisite: CHEM 212 or CHEM 216.

Basic theory and operation of the high-field Fourier transform nuclear magnetic resonance spectrometer. Credit/No Credit grading only. 1 laboratory. Prerequisite: CHEM 319.

Separation, purification, and identification of organic molecules using chemical and instrumental methods, including nuclear magnetic resonance, infrared and ultraviolet spectroscopy and mass spectroscopy, and techniques in high resolution FT-NMR. 1 lecture, 2 laboratories. Prerequisite: CHEM 319.

Oral presentation of current developments in chemistry based on current literature. Preparation for employment and for independent work, including senior project, in chemistry. 2 seminars. Prerequisite or corequisite: CHEM 359 and junior standing.

Extended report on a topic from either an elective laboratory course or an off-campus laboratory experience. Consent of a supervising faculty member must be obtained prior to enrollment in the laboratory course or the off campus experience. Minimum 30 hours time commitment. Prerequisite: CHEM 359, CHEM 459, and consent of instructor.

Completion of a written literature review project under faculty supervision. Written report includes analysis of experimental results presented in the chemical or biochemical literature. Minimum 60 hours time commitment. Prerequisite: CHEM 359, CHEM 459, and consent of instructor.

Completion of a laboratory research project and written report under faculty supervision. Minimum 60 hours time commitment. Total credit limited to 4 units. Prerequisite: CHEM 359, CHEM 459, and consent of instructor.

Advanced laboratory research. Results are presented in a poster session or other public forum. Minimum 60 hours time commitment. Prerequisite: 4 units of CHEM 462 and consent of instructor.

Teaching assignment in an undergraduate college classroom. Includes teaching and related activities under the direction of a permanent faculty member in the Department of Chemistry and Biochemistry. Total credit limited to 4 units. Prerequisite: Junior standing, CHEM 231 (or permission of instructor), evidence of satisfactory preparation in chemistry. Department chair approval required.

Directed group study of selected topics for advanced students. Open to undergraduate and graduate students. Class Schedule will list topic selected. Total credit limited to 6 units. 1 to 3 lectures. Prerequisite: CHEM 305, or CHEM 351, or CHEM 217 or consent of instructor.

Theory and practice of immunochemistry including the structure, genetics, chemical modification and production of antibodies, immunochemical techniques and the biochemistry of the immune defense process. 3 lectures. Prerequisite: CHEM 371 or consent of instructor.

Experiments in protein affinity chromatography, electrophoresis and blotting, immunoprecipitation techniques, antibody-enzyme conjugation, and immunoassay. 2 laboratories. Prerequisite: CHEM 313 or CHEM 371.

Introduction to the principles and methods of tissue culture with emphasis on the manipulation and study of animal cells. 2 lectures, 2 laboratories. Prerequisite: MCRO 224, BIO 303 or BIO 351 and CHEM 313 or CHEM 371.

Consideration of current selected topics in pharmacology including drug design, biochemical mechanisms of drug activity and issues pertaining to the disposition of drugs to the public. Lecture, professional consultation, library research, and student presentations. 3 lectures. Prerequisite: CHEM 377 or equivalent as determined by instructor.

A systematic study of chemical and physical properties of inorganic compounds based on periodic groupings with emphasis on chemical bonding and structure. Topics will include coordination chemistry and kinetics, organometallic chemistry, advanced acid-base relationships and bonding theories plus other selected topics. 3 lectures. Prerequisite: CHEM 306, or CHEM 352, and CHEM 231 or consent of instructor.

Synthetic methods involving the preparation and characterization of a variety of inorganic, organometallic and coordination compounds employing high temperature, inert atmosphere, photolytic, electrolytic and other synthetic techniques. 1 laboratory. Prerequisite or concurrent: CHEM 481.

Part-time work experience in business, industry, government, and other areas of student career interest. Positions are paid and usually require relocation and registration in course for two consecutive quarters. Formal report and evaluation by work supervisor required. 2 units only applicable to approved chemistry electives. Total credit limited to 16 units. Credit/No Credit grading only. Prerequisite: Sophomore standing and consent of instructor.

Full-time work experience in business, industry, government, and other areas of student career interest. Positions are paid and usually require relocation and registration in course for two consecutive quarters. Formal report and evaluation by work supervisor required. 2 units only applicable to approved chemistry electives. Total credit limited to 16 units. Credit/No Credit grading only. Prerequisite: Sophomore standing and consent of instructor.

Nutritional aspects of biochemistry. Lecture, library research and student presentations. Topics include vitamins and minerals, essential and energy providing nutrients, deficiency, degenerative and genetic diseases of metabolism. Emphasis on current research and controversy. 3 lectures. Prerequisite: CHEM 313 or CHEM 372 or consent of instructor.